Dopamine transporter (DAT) inhibitors may represent a promising class of drugs in the development of cocaine pharmacotherapies. In the present study, the effects of pretreatments with the selective DAT inhibitor 3beta-(4-chlorophenyl)tropane-2beta-[3-(4'-methylphenyl)isoxazol-5-yl] hydrochloride (RTI-336) (0.3-1.7 mg/kg) were characterized in rhesus monkeys trained to self-administer cocaine (0...

Reflectance Transformation Imaging (RTI) is a technique for estimating surface local angular reflectance from set of stereo-photometric images captured with variable lighting directions. The digitization this information fully fits into the industry 4.0 approach and makes it possible to characterize visual properties surface. proposed method, namely HD-RTI, based on coupling RTI HDR imaging tec...

Introduction Road Traffic Injury is common cause of unintentional injury globally and Low and middle income countries account for 90% of 1.3 million Road Traffic Injury (RTI) deaths. In Africa region, Nigeria accounts for 25% of RTI mortality but has no comprehensive and reliable RTI surveillance system. Data from Federal Road Safety Commissions (FRSC) shows gaps in RTI reporting with large dis...

BACKGROUND Respiratory tract infections (RTIs) are an important cause of death in children, and often contribute to the terminal decline in children with chronic conditions. RTIs are often underrecorded as the underlying cause of death; therefore the overall contribution of RTIs to child deaths and the potential preventability of RTI-related deaths have not been adequately quantified. METHODS...

Injured alveolar epithelial type (AT) I cells are replaced following the proliferation and transformation of ATII cells to new ATI cells. RTI(40) is an ATI cell-specific protein required for normal lung development. We hypothesized that intermediate cell types in the ATII-to-ATI cell transformation would coexpress RTI(40) and ATII cell-selective proteins. To test this hypothesis, we used a rat ...

OBJECTIVE/SETTING To provide a population-based analysis of childhood road traffic injuries (RTI) in two communities of the greater Accra region of Ghana, with the goal of establishing an RTI incidence baseline in these communities and to identify RTI characteristics in order to model a targeted injury prevention programme. STUDY DESIGN Geographical cluster sampling was performed in two separ...

Quantitative measurement of reverse transcriptase-inhibiting (RTI) antibodies in Japanese household cats naturally infected with feline immunodeficiency virus (FIV) was performed by poly A-linked colorimetric reverse transcriptase assay (PAC-RTA). Eight FIV-seropositive plasma samples were diluted twofold from 1:10 to 1:160 and incubated with FIV RT. Fifty percent RTI activity (RTI50) was calcu...