Force spectroscopies have emerged as a powerful and unprecedented tool to study and manipulate biomolecules directly at a molecular level. Usually, protein and DNA behavior under force is described within the framework of the worm-like chain (WLC) model for polymer elasticity. Although it has been surprisingly successful for the interpretation of experimental data, especially at high forces, th...

We develop an analytical method for studying the properties of a noninteracting wormlike chain (WLC) in confined geometries. The mean-field-like theory replaces the rigid constraints of confinement with average constraints, thus allowing us to develop a tractable method for treating a WLC wrapped on the surface of a sphere, and fully encapsulated within it. The efficacy of the theory is establi...

Firefighters are exposed to many traumatic events. The psychological costs of this exposure increase the risk of Post-Traumatic Stress disorder (PTSD), depression and anxiety. This study examined the effectiveness of Narrative Exposure Therapy (NET) as a short-term treatment for reducing PTSD symptoms among Saudi firefighters. A randomized waiting-list control study was conducted with 34 trauma...

Implication for health policy/practice/research/medical education: Novel optical imaging technologies have shown promising results for the diagnosis, management and follow up of bladder cancer. They might take the place of the white light cystoscopy which is the gold standard for many decades. Bladder cancer is diagnosed and followed-up with cys-toscopy as the " gold standard ". For many decade...

در این مقاله بهینه­سازی مقید تابع هدف کمپرسور محوری با استفاده از روش الگوریتم ژنتیک مورد مطالعه قرار گرفته است. با استفاده از  روش وزنی و اثر تغییر ترکیب­های متفاوت ضرایب وزنی تابع هدف، بهینه­سازی کمپرسور محوری مورد بررسی شده است. تابع هدف شامل ترکیب خطی بازده آیزنتروپیک و ضریب افزایش فشار استاتیک با درنظر گرفتن سه متغیر قطر متوسط طبقه ی کمپرسور، زاویه هوا در ورود به روتور و ضریب جریان می­باشد...