PURPOSE To determine whether damage to neonatal brain is exacerbated with multiple mild cerebral insults as detected with MRI and corroborated using histology. MATERIALS AND METHODS The combined brain injury produced by multiple procedures was compared in neonatal rats having: Sham surgery at P5, Sham surgery at P5 plus a diffuse mild transient unilateral cerebral hypoxia ischemia (HI) at P7,...

Neutral intergalactic clouds are so greatly out numbered by galaxies that their integral HI content is negligible in comparison to that contained in optically luminous galaxies. In fact, no HI cloud that is not associated with a galaxy or grouping of galaxies has yet been identified. This points to a causal relationship that relies on gravitational potentials that bind galaxies also being respo...

(or up to 150 million gallons per year) to BioAlternatives as a feedstock for fuel production. The partners plan to locate algae production and biodiesel refinery facilities in Louisiana. In October 2007, the Chevron Corporation announced a collaborative research project with the DoE's National Renewable Energy Laboratory (NREL) to explore the production of transport fuels, including jet fuel, ...

Perinatal hypoxia/ischemia (HI) is a common cause of neurological deficits in children. Our goal was to elucidate the underlying mechanisms that contribute to the neurological sequelae of HI-induced brain injury. HI was induced by permanent ligation of the left carotid artery followed by 90 min of hypoxia (7.8% O2) in female P7 rats. A two-dimensional differential proteome analysis was used to ...

BACKGROUND Screening tests are available to determine immunity to vaccine-preventable diseases, such as mumps and rubella. We aimed to define better assay for detecting immune status of health care personnel to vaccine-preventable diseases. METHODS Mumps and rubella antibodies of health care personnel at Shimane University Hospital were examined by hemagglutination inhibition assay (HI), comp...

The Arecibo Legacy Fast ALFA (ALFALFA) survey is a program aimed at obtaining a census of HI-bearing objects over a cosmologically significant volume of the local universe. When complete in ∼3–4 years, it will cover 7000 square degrees of high latitude sky using the 305 m telescope and the seven-beam Arecibo L-band feed array (ALFA). As of May 1, 2008, almost 60% of the required observations ar...

When is the composition of paraproducts bounded? This is an important, and difficult question. We consider randomized variants of this question, finding non-classical characterizations. For dyadic interval I, let hI = h 0 I be the L-normalized Haar function adapted to I, the superscript 0 denoting that it has integral zero. Set h I = |hI |, the superscript 1 denoting a non-zero integral. A (cla...

BACKGROUND Cerebral hypoxia/ischemia (HI) is not uncommon during the perinatal period. If occurring, it can result in severe neurologic disabilities that persist throughout life. Salvinorin A, a non-opioid Kappa opioid receptors (KOR) selective agonist, has the potential to address this devastating situation. We have demonstrated that salvinorin A administration before HI, preserves pial artery...

While B cells are generally considered to be positive regulators of humoral immune responses due to their ability to differentiate into plasmablasts/plasma cells and produce antibodies, B cells also modulate immune responses through antigen presentation and cytokine secretion. Moreover, "regulatory B cells" that suppress immune responses have been recognized as an important new component of the...