نتایج جستجو برای: شاخص homa ir

تعداد نتایج: 144526  

Journal: :Baghdad Science Journal 2023

Diabetes mellitus caused by insulin resistance is prompted obesity. Neuropeptide Nesfatin-1 was identified in several organs, including the central nervous system and pancreatic islet cells. peptide appears to be involved hypothalamic circuits that energy homeostasis control food intake. Adiponectin a plasma collagen-like protein produced adipocytes have been linked development of (IR), diabete...

Journal: :iranian journal of diabetes and obesity 0
ragaa abdelkader ramadan lecturer of chemical pathology, medical research institute teaching hospital–alexandria university–egypt

abstract objective: homeostasis model assessment of insulin resistance (homa-ir) is a simple and practical method for estimation of insulin resistance (ir), but a reliable reference interval (ri) of homa-ir is needed to deduce the threshold level to define ir. this ri has been controversial in different populations and even more divergent when considering factors like age, gender and body mass ...

2013
Alina Sokup Barbara Ruszkowska-Ciastek Krzysztof Góralczyk Małgorzata Walentowicz Marek Szymański Danuta Rość

BACKGROUND Chronic insulin resistance, exacerbated in the course of pregnancy, is an important pathophysiologic mechanism of gestational diabetes mellitus (GDM). We hypothesise that the degree of insulin resistance, assessed at diagnosis of GDM, is a parameter of its pathophysiologic heterogeneity and/or severity. Thus, it offers potential to open new avenues for the personalization of therapy ...

ژورنال: کومش 2017
زردوز, حمیرا, صادقی محلی, فروزان, مقامی, سهیلا,

هدف: مواجهه با استرس در دوران شیرخوارگی ریسک ابتلا به اختلالات متابولیک، رفتاری و سایکولوژیک در دوره‌های بعدی زندگی را افزایش می‌دهد. در این راستا مطالعه حاضر به بررسی اثر استرس جداسازی از مادر بر غلظت‌های پلاسمایی گلوکز و انسولین و شاخص HOMA-IR (شاخص مقاومت به انسولین) در موش‌های صحرایی نر بالغ پرداخته است. مواد و روش‌ها: حیوانات پس از تولد به دو گروه "با استرس" و "بدون استرس" تقسیم شدند. حیوا...

خسروی, نیکو, سوری, رحمن, منتظری طالقانی, حمیده,

زمینه و هدف: لپتین و آدیپونکتین از جمله آدیپوسایتوکاین های مترشحه از بافت چربی هستند که در پاتوژنز چاقی و اختلالات همراه با آن نقش دارند. پژوهش حاضر تاثیر تمرینات استقامتی و مقاومتی را بر سطح سرمی لپتین، آدیپونکتین و شاخص مقاومت به انسولین (HOMA-IR) در زنان چاق یائسه غیر فعال مورد مطالعه قرار داده است. روش بررسی: این مطالعه یک کارآزمایی بالینی تصادفی سازی شده از نوع کاربردی با روش نیمه تجربی ...

Journal: :AIDS 2012
Mark W Hull Kathleen Rollet Erica E M Moodie Sharon Walmsley Joseph Cox Martin Potter Curtis Cooper Neora Pick Sahar Saeed Marina B Klein

OBJECTIVE Hepatitis C virus (HCV) infection is associated with higher insulin levels and insulin resistance. We evaluated factors associated with insulin resistance in a cohort of HIV/HCV-coinfected patients and determined the effect of insulin resistance on the development of hepatic fibrosis. METHODS Data were analysed from 158 nondiabetic participants in a prospective Canadian cohort of HI...

Journal: :Diabetes care 2002
Vijay Jayagopal Eric S Kilpatrick Paul E Jennings David A Hepburn Stephen L Atkin

OBJECTIVE Individuals with type 2 diabetes are particularly vulnerable to cardiovascular disease. Insulin resistance is a major determinant of this increased risk and is a potential therapeutic target. This study was undertaken to establish the natural biological variation of insulin resistance in individuals with type 2 diabetes. RESEARCH DESIGN AND METHODS The biological variation of insuli...

2011
Mariusz Stepień Kinga Rosniak-Bak Marek Paradowski Malgorzata Misztal Krzysztof Kujawski Maciej Banach Jacek Rysz

BACKGROUND The aim of the study was to estimate the association between anthropometric obesity parameters, serum concentrations of ghrelin, resistin, leptin, adiponectin and homeostasis model assessment (HOMA-IR) in obese non-diabetic insulin-sensitive and insulin-resistant patients. MATERIAL/METHODS Study subjects included 37 obese (body mass index [BMI] ≥ 30 kg/m2) out-clinic patients aged ...

Journal: :Pediatric exercise science 2013
Bumsoo Ahn Robert McMurray Joanne Harrell

The relationship between insulin resistance (HOMA-IR), percent body fat, and aerobic fitness (VO2max per unit fat free mass; mL/kgFFM/min) was examined in 1,710 children. Percent body fat was estimated from sum of skinfolds, and VO2max was estimated from submaximal cycle ergometer tests. Overnight fasting blood samples were obtained. VO2max (mL/kgFFM/min) and percent body fat were correlated wi...

2011
Hui-Qi Qu Quan Li Anne R. Rentfro Susan P. Fisher-Hoch Joseph B. McCormick

OBJECTIVE The lack of standardized reference range for the homeostasis model assessment-estimated insulin resistance (HOMA-IR) index has limited its clinical application. This study defines the reference range of HOMA-IR index in an adult Hispanic population based with machine learning methods. METHODS This study investigated a Hispanic population of 1854 adults, randomly selected on the basi...

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