The Tetrahymena L-21 ScaI ribozyme derived from the self-splicing group I intron catalyzes a reversible reaction analogous to the first step of self-splicing: CCCUCUA (S) + [UC]G right harpoon over left harpoon CCCUCU (P) + [UC]GA. To relate our understanding of the ribozyme to the self-splicing reaction and to further the mechanistic dissection of the ribozyme reaction, we have established a q...

Catheterization and Cardiovascular InterventionsVolume 101, Issue 2 p. i-i ISSUE INFORMATION - COPYRIGHTFree Access Information Copyright First published: 17 February 2023 https://doi.org/10.1002/ccd.30256AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text full-text accessPlease review our Terms Conditions of Use check box below sh...

Abstract Background Cardiogenic shock (CS) includes several phenotypes of congestion or hypoperfusion with heterogenous hemodynamic features. Timely prognostication scoring tools is warranted to identify patients requiring escalation mechanical circulatory support (MCS) and avoid futility. Purpose Accordingly, we explored the role updated Society for Cardiovascular Angiography Interventions (SC...

2009;53;76-90; originally published online Dec 8, 2008; J. Am. Coll. Cardiol. Thomas, Peter L. Tilkemeier, and Wm. Guy Weigold Rosenthal, Harry Solomon, Arthur E. Stillman, Shawn D. Teague, James D. E. Kahn, Jr, Gerard R. Martin, Frederick A. Masoudi, Eric D. Peterson, Geoffrey L. McB. Hodgson, Udo Hoffmann, Robert J. Horn, III, W. Gregory Hundley, Charles Pamela S. Douglas, Robert C. Hendel, J...

In the United States alone, there are currently approximately 14.5 million cancer survivors, and this number is expected to increase to 20 million by 2020. Cancer therapies can cause significant injury to the vasculature, resulting in angina, acute coronary syndromes (ACS), stroke, critical limb ischemia, arrhythmias, and heart failure, independently from the direct myocardial or pericardial da...