In this work we use EBT3 film measurements at 10 MV to demonstrate the suitability of the Exradin W1 (plastic scintillator) for relative dosimetry within small photon fields. We then use the Exradin W1 to measure the small field correction factors required by two other detectors: the PTW unshielded Ediode 60017 and the PTW microDiamond 60019. We consider on-axis correction-factors for small fie...

INTRODUCTION Patients undergoing surgery frequently develop neuropsychological disturbances, including cognitive decline or memory impairment, and routine clinical procedures such as mechanical ventilation (MV) may affect acute-phase brain outcome. We aimed to investigate the effect of the prolonged MV on postoperative memory dysfunction in surgical mice. METHODS Male C57BL/6 mice were random...

MYBPC3 mutations cause hypertrophic cardiomyopathy, which is frequently associated with mitral valve (MV) pathology. We reasoned that increased MV size is caused by localized growth factors with paracrine effects. We used high-resolution echocardiography to compare Mybpc3-null, heterozygous, and wild-type mice (n = 84, aged 3-6 months) and micro-CT for MV volume (n = 6, age 6 months). Mybpc3-nu...

BACKGROUND This study was designed to evaluate the integral dose (ID) received by normal tissue from intensity-modulated radiotherapy (IMRT) for prostate cancer. METHODS AND MATERIALS Twenty-five radiation treatment plans including IMRT using a conventional linac with both 6 MV (6MV-IMRT) and 20 MV (20MV-IMRT), as well as three-dimensional conformal radiotherapy (3DCRT) using 6 MV (6MV-3DCRT)...

2.5 MV electronic portal imaging, available on Varian TrueBeam machines, was characterized using various phantoms in this study. Its low-contrast detectability, spatial resolution, and contrast-to-noise ratio (CNR) were compared with those of conventional 6 MV and kV planar imaging. Scatter effect in large patient body was simulated by adding solid water slabs along the beam path. The 2.5 MV im...

Most of the treatment units, both new and old models, are equipped with a megavoltage portal imager but its use for volumetric imaging is limited. This is mainly due to the poor image quality produced by the high-energy treatment beam (> 6MV). A linac at our center is equipped with a prototype 2.5 MV imaging beam. This study evaluates the feasibility of low-dose megavoltage cone-beam imaging wi...

Many viruses have been reported to be associated with rash development. Multiplex real-time PCR was used to investigate the presence of 5 viruses associated with rashes: measles virus (MV), rubella virus (RV), human parvovirus B19 (PVB19), human herpes virus 6 (HHV-6), and HHV-7. A total of 187 clinical specimens from 169 patients with erythema were collected between January 2006 and Decembe...

OBJECTIVE To determine effect of maternal antibodies on immune response to oral vaccination against rabies in young foxes. ANIMALS 250 cubs from 48 vixens. PROCEDURE Sera were obtained from cubs of 36 vaccinated (maternally vaccinated [MV+]) and 12 nonvaccinated (MV-) vixens between 23 and 71 days of age and tested for neutralizing antibodies. Seventy-one MV+ cubs and 33 MV-cubs were vaccin...

introduction for dose measurement in megavoltage (mv) photon beams with ion chambers, the effect of volume occupied by the air cavity is not negligible. therefore, the result of measurement should be corrected with a displacement perturbation correction factor (pdis) or using an effective point of measurement (epom). the aim of this study is to calculate the epom for cylindrical ion chamber and...