Exogenously supplied ascorbic acid (AsA) strongly induced furanocoumarin production in leaf and root cultures of GLEHNIA LITTORALIS, but not in cell suspension cultures, after 24 h of treatment. The dose dependency showed that both organ tissues responded well to AsA supplied at concentrations of 10 - 40 mM. For induction of furanocoumarin production, roots required contact with AsA for at leas...

As frações solúveis em hexano dos rizomas ou das folhas de cinco espécies do gênero Dorstenia (Moraceae) (D. bahiensis Kl., D. bryoniifolia Mart ex. Miq., D. carautae C.C.Berg., D. cayapiaa Vell. e D. heringerii Car. & Val.) foram analisadas por HRGC-MS (cromatografia gasosa de alta resolução acoplada a espectrometria de massas). Foram identificados triterpenos pentacíclicos, esteróides e furoc...

امروزه علاقه به اعمال سبک مربی گری در میان مدیران سازمانها حال رشد است. سازمان ها دنبال این روش مدیریتی هستند تا با استفاده از شایستگی های گری، نیروی انسانی خود را متعهد ساخته و بهبودعملکرد فردی سازمانی نائل آیند. وجود این، هیچ تحقیق یا ادبیاتی زمینه ندارد که کدامیک عوامل بیشترین بهبود عملکرد برای ویژه بانک بوجود می آورند. حاضر راستای پاسخگویی چالش، صورت جامع نظام مند تمامی شاخص هایی حوزه موثر ...

سابقه و هدف: امروزه صنعتی شدن توسعه شهرنشینی باعث آلودگی هوا در اکثر کلان‌شهرهای جهان شده است سالانه میلیون­ ها نفر به ­علت جان خود را از دست می­ دهند. ﺑﺎ ﺗﻮﺟﻪ ﺑﻪ ﻣﺤﺪود ﺑﻮدن ﺷﺒﻜﻪ اﻳﺴﺘﮕﺎه‌ﻫﺎى ﭘﺎﻳﺶ آﻻﻳﻨﺪه‌ﻫﺎى ﻫﻮا ﻏﻴﺮ اﻗﺘﺼﺎدى اﻓﺰاﻳﺶ ﺗﻌﺪاد این اﻳﺴــﺘﮕﺎه‌ﻫا سطح شهرها، دﺳﺖ‌ﻳﺎﺑﻰ ﭘﻮﺷــﺶ ﻣﻜﺎﻧﻰ زﻣﺎﻧﻰ ﻣﻨﺎﺳــﺐ برای ﻧﺸﺎن دادن ﺗﻐﻴﻴﺮات ﻏﻠﻈﺖ ذرات آلاینده ﺑﺴﻴﺎر دﺷﻮار اﺳﺖ. بر اساس پژوهش حاضر با هدف تهیه نقشه ­ها...

Furocoumarin-induced DNA damage, monoadducts, and cross-links were measured in normal human, xeroderma pigmentosum, and Fanconi's anemia cells after exposure to near-UV (356 nm). At similar concentrations and near-UV doses, photoaddition by 8-methoxypsoralen was twice that by angelicin and the substitution of bromodeoxyuridine for thymidine in one strand of DNA did not alter the binding. The ra...

Real-time fluorescence detection systems were adapted to identify DNA adducts formed by photogenotoxic phytochemicals. Two assays were developed: the first was based on quantitative polymerase chain reaction (qPCR) while the second used thermal denaturation and renaturation (D-R). Both assays employed yeast DNA, the fluorescent dye SYBR Green and a real-time PCR thermocycler. The furanocoumarin...

Abstract Introduction The Giant Hogweed (Heracleum mantegazzianum) is a rare cause for chemical burns in humans and animals acquiring growing recognition mainstream media as relevant public health concern. Injuries attributed to this plant range from innocuous superficial irritation full-thickness burns. A vast majority of cases will resolve with conservative measures effective first aid, but t...

Angelica archangelica fruits were collected from 64 locations around Iceland and analysed for furanocoumarins by high-performance liquid chromatography. The average furanocoumarin content was found to be 22.5 mg/g, ranging from 14.0 to 31.6 mg/g. Whereas imperatorin was the main compound in all samples, the order of other compounds was highly diverse. Considerable differences were observed betw...