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Although widely used, pharmacotherapeutic approaches to the treatment of post-traumatic stress disorder (PTSD) have been undermined by uncertainty about efficacy. Hoskins et al (pp. 93–100) systematically reviewed the relevant literature and found that selective serotonin reuptake inhibitors (SSRIs) appear to be superior to placebo in reducing PTSD symptoms but with a small associated effect si...

Poor compliance can reduce the efficacy of treatments, resulting in worse health outcomes for patients. Using a randomised design, Gray et al (pp. 157–162) trained community psychiatric nurses for 80 hours in medication management. Independent researchers interviewed their patients and the patients of nurses who did not receive training, at recruitment and 6 months later. Patients who were care...

I. Disease Description Measles is an acute viral illness caused by a virus in the family paramyxovirus, genus Morbillivirus. Measles is characterized by a prodrome of fever (as high as 105°F) and malaise, cough, coryza, and conjunctivitis, followed by a maculopapular rash.1 The rash spreads from head to trunk to lower extremities. Measles is usually a mild or moderately severe illness. However,...

DNA/RNA Description 2573 base-pairs, starts at 7163223 and ends at 7165795 bp from pter with minus strand orientation. Transcription This gene contains 4 exons and 3 introns. The transcription produces 3 alternatively spliced mRNA variants: variant 1 (NM_001307.5) encodes the longer isoform; variant 2 (NM_001185022.1) has an alternate 5' UTR sequence; variant 3 (NM_001185023.1) lacks an exon in...