Fanconi anemia (FA) is a rare disorder characterized by physical abnormalities, bone marrow failure (BMF), increased risk of malignancies, and cellular hypersensitivity to DNA cross-linking agents. This study evaluated the genetic alterations in three major Fanconi genes (FANCA, FANCC, and FANCG) in 30 FA patients using multiplex ligation-dependent probe amplification and direct sequencing. Thi...

In framework of variational method with a single trial function an accurate study of the lowest gerade 1g and ungerade 1u electronic states of the molecular ion H 2 in a magnetic field ranging 0− 4.414× 10 13 G for an arbitrary orientation angle of the molecular axis 0 ≤ θ ≤ 90 is performed. Oneparametric gauge dependence in the Hamiltonian is introduced then variationally optimized. A well pro...

is similar to the proof of Theorem 2.4 ((rst direction), together with the second part of Lemma 4.3 that guarantees that D 1 (e) = D 1 (e f) D 1 (e g). Using the last two theorems, we get Let us now brieey discuss the case of computing general relations and not necessarily functions. The equality in Lemma 4.3 part (1), does not hold anymore. However, by FKN91] the two sides cannot be too far. A...

OBJECTIVE The aim of this study was to investigate the association of functional MMP-1-1607 1G/2G and MMP-9-1562 C/T gene polymorphisms with spontaneous preterm birth (SPTB; preterm birth with intact membranes) in European Caucasian women, as well as the contribution of these polymorphisms to different clinical features of women with SPTB. METHODS AND PATIENTS A case-control study was conduct...

BACKGROUND Bioethanol can be produced from sugar-rich, starch-rich (first generation; 1G) or lignocellulosic (second generation; 2G) raw materials. Integration of 2G ethanol with 1G could facilitate the introduction of the 2G technology. The capital cost per ton of fuel produced would be diminished and better utilization of the biomass can be achieved. It would, furthermore, decrease the energy...

A parallel version of an algorithm for solving systems of integer linear equations with f0; 1g-variables is presented. The algorithm is based on lattice basis reduction in combination with explicit enumer-ation. 1 The algorithm A parallel version of an algorithm proposed by Kaib and Ritter 4] has been implemented with PVM to nd all f0; 1g-solutions of integer linear equation systems. For exampl...

We describe a molecular analysis of 184 cystic fibrosis (CF) families in Wales. To determine accurate frequency data for the CF mutations in the Welsh population, families with at least three Welsh grandparents were strictly regarded as Welsh. Of these 74 families, we have identified approximately 90% of mutations causing CF, with delta F508 accounting for 71.8% and 621 + 1G greater than T 6.7%...

The field effects of buoyancy on laminar and turbulent premixed v-flames have been studied by the use of laser Doppler velocimetry to measure the velocity statistics in +1g, -1g and μg flames. The experimental conditions covered mean velocity, Uo, of 0.4 to 2 m/s, methane/air equivalence ratio, φ, of 0.62 to 0.75. The Reynolds numbers, from 625 to 3130 and the Richardson number from 0.05 to 1.3...

BACKGROUND Reports of neuroleptic malignant syndrome (NMS) induced by second-generation antipsychotic drugs highlight a propensity for atypical clinical presentations. AIMS To systematically compare the clinical profile of NMS induced by first- (1G-NMS) and second-generation antipsychotic drugs (2G-NMS). METHOD The Australian Adverse Drug Reaction Advisory Committee (ADRAC) database was sea...

The interaction of an animal with its environment during a critical period in early postnatal life has lifelong effects on the structure and function of sensory and motor systems. To gain insight into the molecular mechanisms of experience-dependent development, we challenged young rats to adapt to a new environment that engenders novel motor behavior. Rats born in the gravitational field (1G) ...