نتایج جستجو برای: نقطه pc6

تعداد نتایج: 20807  

Journal: :FEBS letters 2003
Nadim Srour Annie Lebel Stephanie McMahon Isabelle Fournier Martin Fugère Robert Day Claire M Dubois

Proprotein convertases (PCs) have been proposed to play a role in tumor necrosis factor-alpha converting enzyme (TACE) processing/activation. Using the furin-deficient LoVo cells, as well as the furin-proficient synoviocytes and HT1080 cells expressing the furin inhibitor alpha(1)-PDX, we demonstrate that furin activity alone is not sufficient for effective maturation and activation of the TACE...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 1997
F I Raynaud F E Boxall P M Goddard M Valenti M Jones B A Murrer M Abrams L R Kelland

A novel sterically hindered platinum complex, AMD473 [cis-amminedichloro(2-methylpyridine) platinum(II)], designed primarily to be less susceptible to inactivation by thiols, has shown in vitro activity against several ovarian carcinoma cell lines. Notably, AMD473 has shown activity in vitro in human carcinoma cells that have acquired cisplatin resistance due to reduced drug transport (41M/41Mc...

Journal: :Biomedicine 2023

Background: Embryo implantation is a complex biological process which requires synchronized dialogue between the receptive endometrium and blastocyst. The endometrium, however, only to embryo for very short period. Recurrent failure (RIF) major challenge in assisted reproductive techniques mainly due impaired receptivity, but there still need reliable valid clinical test assess endometrial rece...

ژورنال: :hormozgan medical journal 0
کریم ناصری k naseri گروه بیهوشی و مراقبتهای ویژه، بیمارستان بعثت، دانشگاه علوم پزشکی کردستان، سنندج، ایران شعله شامی sh shami بهزاد احسن b ahsan محمدرضا زجاجی کهن m.r zojaji kohan

مقدمه: تهوع و استفراغ از جمله شایع ترین عوارض بعد از عمل جراحی هستند. برای رفع عارضه در کنار تداخلات دارویی سایر روشهای بهداشتی طب جایگزین نیز جهت کمک به بیماران ابداع شده اند. این مطالعه برای تاثیر طب فشاری به عنوان یک روش بالقوه سالم نسبت به سایر روشهای موجود استفاده از دارو جهت جلوگیری و یا کاهش تهوع و استفراغ بعد از عمل جراحی انجام شده است. روش کار: این مطالعه به صورت مداخله ای تجربی دو سو ...

2015
Ning Wang Sheng-Feng Lu Hui Chen Jian-Fei Wang Shu-Ping Fu Chen-Jun Hu Yi Yang Fan-Rong Liang Bing-Mei Zhu

BACKGROUND Angina pectoris (Angina) is a medical condition related to myocardial ischemia. Although acupuncture has been widely accepted as a clinical approach for angina, there is no sufficient evidence of its effectiveness against this syndrome, and its mechanisms have not yet been well elucidated. We develop this protocol to confirm the clinical efficacy of electro-acupuncture on stable angi...

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