OBJECTIVE The attitudes of girls regarding menarche vary according to their cultural backgrounds. Asian girls may hesitate to discuss menarche. Computer-assisted self-administered interviewing (CASI) is considered a valid and effective tool for investigating the timing of menarche; however, the validity of self-reported menarche data from CASI in Chinese culture is currently unknown. We aimed t...

This study focuses on the physical vulnerability of buildings to flash floods using an indicator-based methodology. A index (PhVI) that combines intrinsic (IV) and flood intensity (FFI) is proposed. IV evaluates propensity suffer damage, resulting from indicators related building properties. FFI estimates potential cause flow parameters. PhVI was applied a critical section small drainage basin ...

Background Early and accurate diagnosis of fatal familial insomnia (FFI) is critical for effective screening; however, this rare disease remains difficult to recognize. This work aimed propose a new diagnostic criterion with optimal sensitivity, specificity, likelihood ratio. Methods An international group experts was established 128 genetically confirmed FFI cases 281 non-FFI prion controls ar...

Cerebellar feedforward inhibition (FFI) is mediated by two distinct pathways targeting different subcellular compartments of Purkinje cells (PCs). The axon of the granule cell, the parallel fiber, makes excitatory synapses not only onto PCs but also onto two types of interneurons, basket and stellate cells. Basket and stellate cells then send inhibitory signals to the soma and dendrites of Purk...

Neurons receive a large number of excitatory and inhibitory synaptic inputs whose temporal interplay determines the spiking behavior. On average, excitation and inhibition balance each other, such that spikes are elicited by fluctuations [1]. In addition, it has been shown in vivo that excitation and inhibition are correlated, with inhibition lagging excitation only by few milliseconds (∼6 ms),...

FFI, a rare prion disease, constitutes by their wake and sleep abnormalities a unique pathophysiological model of disease. Recently, a neurobiological-mathematical model of the human sleep/ wake cycle (MMSWC) developed by Rempe, BestJ and Terman, reconciles circadian/homeostatic influences with new findings like the proposed sleep/wake flip-flop switch and REM-NoREM switch. We attempt now to mo...

Throughout the development of psychology the delineation of personality has played a central role. Together with the NEO-PI-R, a questionnaire derived from the Five Factor Model of Personality, and recent advances in research technology it is now possible to investigate the relationship between personality features and neurophysiological brain processes. The NEO-FFI, the short version of the NE...

BACKGROUND While the construct of integrity has emerged as a front-runner amongst the desirable attributes to select for in medical school admissions, it is less clear how best to assess this characteristic. A potential solution lies in the use of Situational Judgement Tests (SJTs) which have gained popularity due to robust psychometric evidence and potential for large-scale administration. Thi...

We consider the role of physical form, prior experience, and form focused instruction (FFI) in adult language learning. (1) When presented with competing cues to interpretation, learners are more likely to attend to physically more salient cues in the input. (2) Learned attention is an associative learning phenomenon where prior-learned cues block those that are experienced later. (3) The low s...

By initially presenting FFI and its operations analysis (OA) activity, this paper illustrates the use of OA computing at FFI in three ways, in defense analysis, Simula, and various analyses of air defense. The paper focuses on methods, particularly the use of discrete event simulation. Most examples are from 1978–1995, and Simula’s role is highlighted.