AIMS Functional mitral regurgitation (FMR) contributes to morbidity and mortality in heart failure (HF) patients. The aim of this study was to determine whether percutaneous mitral annuloplasty could safely and effectively reduce FMR and yield durable long-term clinical benefit. METHODS AND RESULTS The impact of mitral annuloplasty (Carillon Mitral Contour System) was evaluated in HF patients...

9 We propose a novel method using Bayesian networks to learn the 10 structure of effective connectivity among brain regions involved in a 11 functional MR experiment. The approach is exploratory in the sense 12 that it does not require an a priori model as in the earlier approaches, 13 such as the Structural Equation Modeling or Dynamic Causal 14 Modeling, which can only affirm or refute the co...

When studying complex cognitive tasks using functional magnetic resonance (fMR) imaging one often encounters weak signal responses. These weak responses are corrupted by noise and artifacts of various sources. Preprocessing of the raw data before the application of test statistics helps to extract the signal and thus can vastly improve signal detection. We discuss artifact sources and algorithm...

BACKGROUND Parasites can cause energetically costly behavioural and immunological responses which potentially can reduce host fitness. However, although most laboratory studies indicate that the metabolic rate of the host increases with parasite infestation, this has never been shown in free-living host populations. In fact, studies thus far have shown no effect of parasitism on field metabolic...

Alzheimer's disease and Fragile X syndrome both display synaptic phenotypes, and based on recent studies, likely share dendritic over expression of amyloid precursor protein (APP) and beta-amyloid (Abeta). In order to create a mouse model to specifically study the effects of APP and Abeta at synapses, we crossed Tg2576, which over-express human APP with the Swedish mutation (hAPPsw), with fmr-1...

Blood oxygen level–dependent functional MR (BOLD fMR) imaging, long accepted as a powerful research technique in the cognitive sciences and neurosciences, recently has gained acceptance as a clinical tool. Clinical applications of BOLD imaging have focused primarily on the preoperative locali-zation of the motor, sensory, and language centers of the brain in anticipation of tumor or vascular ma...

Background: Acute effects of positive airway pressure (PAP) [including continuous PAP (CPAP) and adaptive servo-ventilation, an advanced form of bi-level PAP] on functional mitral regurgitation (fMR) in patients with heart failure (HF) with left ventricular (LV) systolic dysfunction remain unclear. Thus, whether PAP therapy reduces fMR in such patients with HF was investigated. Methods and Resu...

A 70-year-old man with hydrocephalus was examined with functional magnetic resonance (fMR) imaging before and after ventriculoperitoneal shunting. Preoperatively, activation by right hand exercise revealed only a slight signal increase in the peri-rolandic area. However, 3 months after ventriculoperitoneal shunting, a significant signal increase was observed. fMR imaging may detect activity-rel...

Ferromagnetic resonance was used to study the temperature dependence of mixed manganese-cobalt ferrite nanoparticles with a size range between 5 and 42 nm synthesized by hydrothermal method. Structural characterization carried out using X-ray diffraction, scanning, transmission electron microscopy. M(H) curves as function Mn2+ content at 2.5 300 K, FMR in 80 < T 700 K were for magnetic characte...

[1] Identification of the mineral remains of magnetotactic bacteria (MTB), known as magnetofossils, is of particular interest because their occurrence can be used for environmental and climatic reconstructions. Single‐domain magnetite particles, which are biomineralized in the cell body of MTB, have characteristic properties that can be used to detect their fossil remains. Acquisition of anhyst...