نتایج جستجو برای: ژن peroxiredoxin

تعداد نتایج: 17682  

2017
Rui D.M. Travasso Fernando Sampaio dos Aidos Anahita Bayani Pedro Abranches Armindo Salvador

Hydrogen peroxide (H2O2) is a key signaling agent. Its best characterized signaling actions in mammalian cells involve the early oxidation of thiols in cytoplasmic phosphatases, kinases and transcription factors. However, these redox targets are orders of magnitude less H2O2-reactive and abundant than cytoplasmic peroxiredoxins. How can they be oxidized in a signaling time frame? Here we invest...

Journal: :Free Radical Biology and Medicine 2021

Many studies reported that redox enzymes, particularly thioredoxin and peroxiredoxin, can be released by cells act as soluble mediators in immunity. Recently, it became clear peroxiredoxins secreted via the exosome-release route, yet remains unclear how this exactly happens why. This review will first introduce briefly possible states of protein cysteines role enzymes their regulation. We then ...

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