PURPOSE After total mesorectal excision (TME) for rectal cancer, pathology is standardized with margin status as a predictor for recurrence. This has yet to be implemented after transanal endoscopic microsurgery (TEM) and was investigated prospectively for T1 rectal adenocarcinomas. PATIENTS AND METHODS Eighty patients after TEM were compared to 75 patients after TME. The study protocol inclu...

Transmission electron microscopy (TEM) is a powerful tool for the investigation of the microstructure of materials, providing crystallographic information and composition at the nanometer scale. For such studies, samples should be transparent to the electron beam. In this review, TEM sample preparation techniques for different classes of materials, such as metals and alloys, multilayered coatin...

Transanal endoscopic microsurgery may be considered medically necessary for treatment of clinical T1 rectal adenocarcinomas than cannot be removed using other means of local excision and that meet all of the following criteria:  Located in the middle or upper part of the rectum  Well or moderately differentiated (G1 or G2)  Without lymphadenopathy or microscopic angiolymphatic invasion  Les...

Widespread use of beta-lactam antibiotics has promoted the evolution of beta-lactamase mutant enzymes that can hydrolyze ever newer classes of these drugs. Among the most pernicious mutants are the inhibitor-resistant TEM beta-lactamases (IRTs), which elude mechanism-based inhibitors, such as clavulanate. Despite much research on these IRTs, little is known about the structural bases of their a...

The sequences of the bla(TEM) genes encoding TEM-92 in Proteus mirabilis and Providencia stuartii isolates were determined and were found to be identical. Except for positions 218 (Lys-6) and 512 (Lys-104), the nucleotide sequence of bla(TEM-92) was identical to that of bla(TEM-20), including the sequence of the promoter region harboring a 135-bp deletion combined with a G-162-->T substitution....

nano world daily. in this paper the lens culinaris seed extract was assessed for thegreen synthesis of silvernanoparticlesat temperature of 25◦c. the nanoparticles were characterized using inductively coupledplasma spectrometry (icp), x-ray diffraction (xrd) and transmission electron microscopy (tem). thenthe antimicrobial activities of these nanoparticles were investigated. p. aeruginosa and s...