100 000 quinacrine nonsurgical female sterilizations have been completed over the past decade involving transcervical insertion of quinacrine (252 mg) as pellets by one, two or three monthly insertions. No deaths have been reported and serious complications are far fewer than for surgical sterilization. Sideeffects are mild and transient. Efficacy has improved from 3 pregnancy failures per 100 ...

As we put 2017 behind us, I am dedicating this editorial to the celebration of Canada’s 150 birthday. I was fortunate to be in Ottawa for the month of August where I took in several Canada 150 events and displays, the most memorable and inspiring being MosaïCanada in Gatineau (created by the world famous Mosaïcultures internationales de Montréal http://english.mosaicanada.ca/). So impressed and...

One of the biggest challenges in studying how genes work is understanding their effect on the physiology and anatomy of the body. Existing tools try to address this using indirect features, such as expression levels and biochemical pathways. Here, we present Gene ORGANizer (geneorganizer.huji.ac.il), a phenotype-based tool that directly links human genes to the body parts they affect. It is bui...

In a study of the clinical and immunogenetic profiles of 17 patients with rheumatoid arthritis and thrombocytopenia (platelet count less than 150 000/mm3 (150 x 10(9)/l)) due to gold therapy two clinical patterns were distinguished without knowledge of HLA type: group I, an early precipitous thrombocytopenia (10 patients), and group II, a less dramatic fluctuant fall (seven patients). In group ...

The UK government’s vaccine advisory committee has said that all people on the GP Learning Disability Register should now be invited for a covid-19 as part of priority group 6. The Joint Committee Vaccination and Immunisation (JCVI) adults with other related conditions such cerebral palsy also local authorities help to identify learning disabilities in residential nursing care, well those who ...

2023 is a momentous year for the Quarterly Journal of Royal Meteorological Society (QJ), celebrating its 150th anniversary. The QJ was initiated in 1873 at time when meteorological science growing rapidly scope and importance one first atmospheric journals to be established. had not yet been recognised with use "Royal" title (that bestowed by Queen Victoria 1883). International Organization als...