Changes in the cytosolic free Ca" concentration following cell surface receptor activation have been proposed to mediate a wide variety of cellular responses. Using the specific Ca2+ chelator quint as a fluorescent intracellular probe, we measured the Ca" levels in the cytosol of clonal rat pituitary cells, GH 3 cells . We demonstrate that thyrotropin-releasing hormone (TRH) at nanomolarconcent...

Species differences in the in vitro stability of sirolimus was assessed in plasma and whole blood in relation to red blood cell distribution. Fresh blood and plasma samples obtained from humans, rabbits, and rats were aliquoted and spiked with sirolimus. After incubation from 0 to 144 hr in a shaking water bath maintained at 37°C, sirolimus concentrations were quantified by a specific high-liqu...

Mid-trimester, preterm prelabour rupture of the membranes (PPROM) with prolonged oligohydramnios remains a challenge for both obstetricians and neonatologists. Although survival rates have improved, morbidity remains common particularly due to pulmonary insufficiency and pulmonary hypertension. The aetiology of abnormal lung development is unknown but may depend critically on pulmonary vascular...

I first summarize Baltag and Smets’ contribution to this volume, and praise their work. Then I compare the anti-lexicographic plausibility update that they propose to a proposal by Aucher, as an illustration of the difference between a qualitative and a quantitive formulation of updates. I quote Spohn’s original work that is at the root of research in plausibility updates and of the notion of a...

Syntax: P 2 Program TD 2 Type-Declaration T, S, U 2 Type-Name MD 2 Method-Declaration F* 2 Formal-List F 2 Formal B 2 Body D 2 Declaration E 2 Expression g 2 Method-Name E* 2 Expression-List C 2 Command M 2 Main I 2 Identi er N 2 Numeric-literal P ::= TD MD M TD ::= j type I fields ( F* ) j TD1 ; TD2 FD ::= j I : T j FD1 ; FD2 T ::= I MD ::= j method I ( F* ) : T f B g j MD1 ; MD2 F* ::= j F F*...

Ambient visibility is a complex manifestation arising out of interactions among many atmospheric variables, including ambient aerosol load, and region specific geophysical characteristics. To functionally relate visibility impairment in Delhi region during winter months−months marred with poor visibility condi�ons−a novel experiment was designed to relate visibility with ambient aerosol load (P...