•A transwell assay can measure Treg control of effector T-cell migration•Treg enhanced migration toward CCL20 in psoriatic arthritis•Anti-TNF induced suppressed arthritis•Increased Th17:Treg ratio was reversed by anti-TNF arthritis Regulatory T cells (Treg) prevent the sites inflammation, thereby limiting disease progression. We investigated this aspect function using (PsA) as an exemplar chron...

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and Introduction Abstract Nickel allergy can result in both cutaneous and systemic manifestations, and can range from mild to severe symptoms. A severe form of this allergy is the Systemic nickel allergy syndrome, clinically characterized by cutaneous manifestions (contact dermatitis, pompholyx, hand dermatitis dyshydrosis, urticaria) with chronic course and systemic symptoms (headache, astheni...

Any researcher with the most modest public profile is used to being asked for virus samples. Traditionally, we’ve advocated the use of alternatives, especially the EICAR test file, to anyone who doesn’t have access to malware through mainstream, trusted channels, as a way of simulating malware behaviour without the attendant risks of genuinely malicious behaviour. But is the EICAR file really s...

I first summarize Baltag and Smets’ contribution to this volume, and praise their work. Then I compare the anti-lexicographic plausibility update that they propose to a proposal by Aucher, as an illustration of the difference between a qualitative and a quantitive formulation of updates. I quote Spohn’s original work that is at the root of research in plausibility updates and of the notion of a...