A3.1 Laplace Expansion of Determinant and Permanent Definition A3.1.1. Let [n] = {1, . . . , n}, I = {i1, . . . , ik} ⊆ [n] and J = {j1, . . . , jk} ⊆ [n]. If A is an n× n matrix, define the k × k matrix A(I; J) = (ãrs) of A to be the matrix with entries ãrs = airjs . Also define the (n− k)× (n− k) complementary matrix A(I; J), where I and J are the complements of I and J respectively. Instead ...

©2006 British Editorial Society of Bone and Joint Surgery doi:10.1302/0301-620X.88B8. 17555 $2.00 J Bone Joint Surg [Br] 2006;88-B:988-92. Tendon allografts play an important role in tendon and ligament reconstruction, particularly where there is a shortage of suitable available local tissue. Although currently used predominantly for ligament reconstruction around the knee, 1-8 they have occasi...

Malebona Precious Matsoso, b.PharM., is Director, Public Health Innovation and Intellectual Property, World Health Organization, Avenue Appia 20, 1211 Geneva 27, Switzerland (matsosom@ who.int). The author has declared no potential conflicts of interest. Copyright © 2009, American Society of Health-System Pharmacists, Inc., and International Pharmaceutical Federation. All rights reserved. 1079-...

Lisa NisseN, B.Pharm., Ph.D., is Senior Lecturer, School of Pharmacy, The University of Queensland, St. Lucia, Queensland 4072, Australia ([email protected]). Dr. Nissen received an honorarium from the International Pharmaceutical Federation for preparing this article and acting as a working-group facilitator. Copyright © 2009, American Society of Health-System Pharmacists, Inc., and Internati...

©2006 British Editorial Society of Bone and Joint Surgery doi:10.1302/0301-620X.88B1. 16837 $2.00 J Bone Joint Surg [Br] 2006;88-B:8-15. Wound dehiscence after spinal instrumentation presents a challenging problem to the surgeon. 1-8 Soft-tissue complications after operation are most commonly seen in patients with poor nutritional status, in the presence of injury to the spinal cord, following ...

A. H. Kaye, FRACS, Neurosurgery Senior Registrar M. Briggs, MSc, FRCS, Consultant Neurosurgeon Department of Neurological Surgery, Radcliffe Infirmary, Oxford, England. Requests for reprints should be sent to Mr A. H. Kaye. © 1982 British Editorial Society of Bone and Joint Surgery 0301-620X/82/4086-0500 $2.00 Case 2. Computerised tomographic scan showing an intracerebral lesion in the left tem...

We previously reported preliminary results of association of clozapine-induced agranulocytosis (CA) with HLA-B38, DR4, DQ3 in five Ashkenazi Jewish patients and with HLA-DR2, DQ1 in four non-Jewish patients. In the present study, 31 additional patients with CA, 10 Ashkenazi Jewish, and 21 of non-Jewish ancestry, were studied. HLA alleles and haplotypes were compared among 52 patients (33 Ashken...

©2006 British Editorial Society of Bone and Joint Surgery doi:10.1302/0301-620X.88B6. 17524 $2.00 J Bone Joint Surg [Br] 2006;88-B:701-5. In vivo studies have shown that bone morphogenetic proteins (BMPs), transforming growth factor (TGF) beta, insulin-like growth factor (IGF), fibroblast growth factor (FGF), plateletderived growth factor (PDGF) and vascular endothelial growth factor (VEGF) are...

From 1 Cardiovascular Research Center, 2 Department of Physiology and 3 Department of Pharmacology, Temple University School of Medicine, Philadelphia, PA 19140, 4 Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232, 5 Department of Medical Biochemistry, Ehime University School of Medicine, Ehime 791-0301, Japan, 6 Molecular Endocrinology Laboratory, Baker ...

BACKGROUND Human leukocyte antigen (HLA) class I and II genotype is associated with clearance of hepatitis C virus (HCV) infection, but little is known regarding its relation with HCV viral load or risk of liver disease in patients with persistent HCV infection. METHODS High-resolution HLA class I and II genotyping was conducted in a prospective cohort of 519 human immunodeficiency virus (HIV...