A stability indicating reversed phase ultra performance liquid chromatography (RP-UPLC) method was developed for simultaneous determination of ambroxol hydrochloride (AMB), cetirizine hydrochloride (CTZ), methylparaben (MP) and propylparaben (PP) in liquid pharmaceutical formulation. The desired chromatographic separation was achieved on an Agilent Eclipse plus C18, 1.8 μm (50 × 2.1 mm) column ...

The optical rotatory properties of a myeloma globulin, immunoglobulin G (IgG), and a normal individual IgG in the far ultraviolet were investigated by rotatory dispersion, circular dichroism, and absorption spectroscopy. The optical rotatory dispersion of the myeloma immunoglobulin displayed two peaks, one at 205 ml* and the other at 210 rnp, and a trough at 228 mp, a lesser one at 230 mp, and ...

The optical rotatory properties of a myeloma globulin, immunoglobulin G (IgG), and a normal individual IgG in the far ultraviolet were investigated by rotatory dispersion, circular dichroism, and absorption spectroscopy. The optical rotatory dispersion of the myeloma immunoglobulin displayed two peaks, one at 205 ml* and the other at 210 rnp, and a trough at 228 mp, a lesser one at 230 mp, and ...

PURPOSE This study was undertaken to assess serial month-to-month consistency of macular pigment (MP) optical density and serum concentrations of lutein (L) and zeaxanthin (Z). Four healthy subjects aged between 23 and 51 years volunteered to participate in this study. METHODS MP optical density (measured psychophysically using heterochromatic flicker photometry [HFP]), and serum concentratio...

BACKGROUND Dupuytren disease (DD) is a fibroproliferative disorder of the palmar fasciae causing extension deficit and impaired hand function. Treatment with injection of collagenase clostridium histolyticum (CCH) is a nonsurgical treatment method. The aim of this study was to evaluate the difference in efficiency and recurrence at 12-month follow-up when treating metacarpophalangeal (MP) and p...

In order to evaluation of drought resistant indices in barley (Hordeum vulgare L.), 10 barley genotypes evaluated in Completely Randomized Design with three Replications in two conditions, (under drought stress and in normal with irrigation in planting, flowering and grain filling stages) in Islamic Azad University, Miyaneh Branch Research Farm in 2012. Drought tolerant indices basis of yield p...

OBJECTIVE We investigated the in vitro effects of low- and high-dose methylprednisolone (MP) on the cytokine-induced expression of HLA-DR, ICAM-1 and VCAM-1 on human brain microvessel endothelial cells (HBMECs). METHODS Brain endothelium was obtained from microvessels included in the apparently normal white matter of surgical specimens of nine patients. Cells were stained with monoclonal anti...

BACKGROUND The use of methylprednisolone (MP) and other corticosteroids for the treatment of acute liver allograft rejection is associated with severe toxicities in nontarget tissues. Therefore, selective delivery of MP to the liver may improve its efficacy and alleviate its side effects. We investigated the effects of a novel liver-targeted dextran prodrug of MP (DMP) in an orthotopic rat live...