Recibido: 09/07/08. Revisado: 11/07/08. Aceptado: 23/07/08. Ninan T. Mathew. director de la Clínica de Cefalea de Houston. Profesor de Neurología en la Escuela de Medicina Universidad de Texas Houston. Presidente de la Sociedad Internacional de Cefalea, de la sección de cefalea de la Academia Americana de Neurología y del Consejo Americano para educación en cefalea. Es autor de 200 publicacione...

Oxidative stress is considered a major cause of the structural and functional changes associated with auditory pathologies induced by exposure to acute acoustic trauma AAT). In the present study, we examined the otoprotective effects of 2,4-disulfophenyl-N-tert-butylnitrone (HPN-07), a nitrone-based free radical trap, on the physiological and cellular changes in the auditory system of chinchill...

We performed temporal and thermal stability studies on SP3-07, a liquid-stabilized reference material for apolipoprotein (apo) B, selected during the previous phase of the International Federation of Clinical Chemistry project on standardization of apolipoprotein measurements. Results indicate that SP3-07 stored at -70 degrees C has the long-term stability required for a reference material. We ...

A novel alkaliphilic spore-forming bacterium was isolated from the benthic sediments of the highly mineralized steppe Lake Khilganta (Transbaikal Region, Russia). Cells of the strain, designated Х-07-2T, were straight to slightly curved rods, Gram-stain-positive and motile. Strain Х-07-2T grew in the pH range from 7.0 to 10.7 (optimum pH 9.6-10.3). Growth was observed at 25-47 °C (optimum 30 °C...

Aurora kinases play an important role in chromosome alignment, segregation, and cytokinesis during mitosis. In the present study, we used a ligand docking method to explore the novel scaffold of potential Aurora B inhibitors. One thousand compounds from our in-house compound library were screened against the Aurora B structure and one compound, (E)-3-((E)-4-(benzo[d][1,3]dioxol-5-yl)-2-oxobut-3...

Idiosyncratic ximelagatran-induced hepatotoxicity has been reported to be associated with human leukocyte antigen (HLA)-DRB1*07:01 and ximelagatran has been reported to inhibit the binding of the ligand peptide to HLA-DRB1*07:01 in vitro. In order to predict the possible interaction modes of ximelagatran with HLA-DR molecules, in silico docking simulations were performed. Molecular dynamics (MD...

Received July 18, 2011, Revised August 4, 2011, Accepted for publication August 4, 2011 Corresponding author: Kee Suck Suh, M.D., Department of Dermatology, Kosin University College of Medicine, 262 Gamcheon-ro, Seo-gu, Busan 602-702, Korea. Tel: 82-51-990-6145, Fax: 82-51-990-3041, E-mail: [email protected] This is an Open Access article distributed under the terms of the Creative Commons ...

Received:May 18, 2015, Revised:(1st) August 5, 2015, (2nd) October 23, 2015, Accepted:October 23, 2015 Corresponding to:Seung-Cheol Shim, Division of Rheumatology, Department of Medicine, Daejeon Rheumatoid and Degenerative Arthritis Center, Chungnam National University Hospital, 282 Munhwa-ro, Jung-gu, Daejeon 35015, Korea. E-mail:[email protected] *The first two authors contributed equally to...

C. K. Jeong, G.-T. Hwang, D. Y. Park, J. H. Park, Dr. M. Byun, Prof. K. J. Lee Department of Materials Science and Engineering Korea Advanced Institute of Science and Technology (KAIST) 291 Daehak-ro , Yuseong-gu , Daejeon 305-701 , South Korea E-mail: [email protected] Dr. J. Lee, Dr. S. Han, Prof. S. H. Ko Department of Mechanical Engineering Seoul National University 1 Gwanak-ro , Gwanak-g...