ABSTRACT In this work, we perform a Bayesian statistical fit to estimate the mass-to-distance ratio and recessional redshift of 10 different black holes hosted at centre active galactic nuclei, namely galaxies NGC 5765b, 6323, UGC 3789, CGCG 074−064, ESO 558−G009, 2960, 6264, 4388, J0437+2456, 2273. Our general relativistic method makes use positions in sky frequency shift observations water me...

Background: Perinatal arterial ischemic stroke (PAIS) is a leading cause of hemiparetic cerebral palsy. Multiple risk factors are associated with PAIS but studies limited by small sample sizes and complex interactions. Unbiased machine learning applied to larger datasets may enable the development robust predictive models. We aimed use identify compare these existing literature. Methods: Common...

The Josephin domain plays an important role in the cellular functions of ataxin-3, the protein responsible for the neurodegenerative Machado-Joseph disease. We have determined the solution structure of Josephin and shown that it belongs to the family of papain-like cysteine proteases, sharing the highest degree of structural similarity with bacterial staphopain. A currently unique structural fe...

An endogenous protease in fish muscle, cathepsin B, was partially purified and characterized from horse mackerel meat. On SDS-PAGE of the purified enzyme under reducing conditions, main protein bands were detected at 28 and 6 kDa and their respective N-terminal sequences showed high homology to heavy and light chains of cathepsin B from other species. This suggested that horse mackerel cathepsi...