Adenosine triphosphate-sensitive K(+) (KATP) channels play an essential role in glucose-induced insulin secretion from pancreatic β-cells. It was recently reported that the KATP channel is also found in the enteroendocrine K-cells and L-cells that secrete glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1), respectively. In the present study, we investigated t...

The surfaces of ready-to-eat meats are susceptible to postprocessing contamination by Listeria monocytogenes. This study examined and modeled the growth characteristics of L. monocytogenes on cooked ham treated with lactic acid solutions (LA). Cooked ham was inoculated with L. monocytogenes (ca. 10(3) CFU/g), immersed in 0, 0.5, 0.75, 1.0, 1.25, 1.5, and 2.0% LA for 30 min, vacuum packaged, an...

in order to study the effect of soil nitrogen content and water hardness on glyphosate efficacy on common lambsquarter (chenopodium album l.) and redroot pigweed (amaranthus retroflexus l.) control, an experiment was carried out as a completely randomized design in a factorial arrangement with three replications. experimental treatments were included soil nitrogen content (18, 50, 90, 200 and 3...

As early aa 1900, Hedon (1) demonstrated that isotonic solutions of glucose and galactose were absorbed more rapidly than similar solutions of arabinose, an observation suggesting selective absorption of certain hexoses. This observation has been amply confirmed and at least two general groups of sugars delineated, one group of rapidly absorbed sugars (glucose and galactose) and another more sl...

Sucrose- and fructose-enriched diets produce hepatic insulin resistance in rats independently of obesity. In humans, fructose infusion results in impaired insulin regulation of glucose production. The aim of the present study was to identify intrahepatic mediators of sucrose- and fructose-induced hepatic insulin resistance. In study 1, male rats were fed a control diet (STD, 68% of energy from ...

Circulating murine monocytes comprise two largely exclusive subpopulations that are responsible for seeding normal tissues (Gr-1-/CCR2-/CX3CR1high) or responding to sites of inflammation (Gr-1+/CCR2+/CX3CR1lo). Gr-1+ monocytes are recruited to the site of infection during the early stages of immune response to the intracellular pathogen Toxoplasma gondii. A murine model of toxoplasmosis was thu...

A number of unusual and rare carbohydrates were tested as potential inhibitors of various glycosidases, as well as inhibitors of N-linked oligosaccharide processing. The best inhibitors of several arylglycosidases and of glucosidase I were L-xylulose and L-fructose. Both of these sugars showed some inhibitory activity towards yeast alpha-glucosidase but were inactive against beta-glucosidase an...

Fructose' is metabolized in Aerobacter aerogenes primarily through the pathway: fructose -fructose-1-P -. fructose-1,6-P. Previous evidence for this pathway was the detection of an inducible fructose-i-P kinase2, I and the demonstration that a mutant lacking frustose-6-P kinase grew well on fructose but not on glucose, whereas a mutant lacking fructose 1,6-diphosphatase grew on glucose but not ...