lactoferrin is a glycoprotein with molecular weight 80 kda iron-binding bond, which is composed of 690 amino acids. in most mammalian body fluids such as sweat, semen, tears, and saliva and milk neutrophil granules there. bovine lactoferrin gene be associated with susceptibility/resistance to mastitis and even with some economically important production traits. this study was carried out to det...

normal 0 false false false en-us x-none ar-sa previous studies have inspected the associations between adiponectin (adipoq) 276g/t polymorphisms and atherosclerosis, but the results are inconclusive. the aim of this study was to explore the relationship between polymorphism +276 g > t (rs1501299) in adipoq and atherosclerosis. a widespread search was directed to identify all studies on the asso...

background: migraine is a common neurovascular disorder with multifactorial and polygenic inheritance. the aim of this study was to investigate the association of a migraine without aura and ala379val polymorphism of lipoprotein-associated phospholipase a2 (lp-pla2) gene in the iranian population. methods: in this study, 103 migraine patients and 100 healthy controls were enrolled. dna samples ...

backgroundattention deficit hyperactivity disorder (adhd), is a multifactorial disorder and converging evidence has implicated abnormalities of dopamine neurotransmission. the aim of this study was to examine the association of -141 polymorphisms in drd2 gene with adha among iranian-azeri population.materials and methods a case–control association study included 153 patients with attention defi...

nitric oxide is an important vasorelaxant factor that it inhibits platelet adhesion and proliferation of smooth muscle cells. no is synthesized from l-arginine by means of endothelial nitric oxide synthase (enos) which is an isoform of  nitric oxide synthase.in the present study, we examined  possible association between the 27 base pair (bp) repeat  polymorphism in intron 4 of the  enos3 gene ...

conclusions in conclusion, chit1 24 bp duplication might not be a candidate gene for susceptibility to ptb. larger studies are necessary to confirm these findings in various populations. results homozygous wild type, heterozygous and homozygous mutant frequencies of chit1 24 bp duplication polymorphism were 43.9%, 43.9% and 12.2% in controls and 42.8%, 45.1% and 12.1% in ptb patients. we found ...

The growth hormone gene could be an attractive candidate gene for milk production in goats. Single-strand conformation polymorphism was used to identify polymorphism at the goat growth hormone (gGH) gene. For this purpose, genotyping of 90 Talli goat breeds was performed. Nine conformational patterns were observed in exon 4 of the gGH gene, with frequencies of 27.7% for the homozygous pattern (...

Background: Human cornea expresses functional Fas-ligand capable of killing Fas+ activated lymphocytes. Fas expression is partly regulated by -670 A/G polymorphism in the promoter region of Fas gene. Objective: The aim of the present study is to determine the association between Fas-670A/G polymorphism and survival of corneal transplantation. Methods: In 276 graft recipients who mainly underwen...

Background: Unexplained recurrent spontaneous abortion (URSA) has been suggested being associated with the failure of fetal-maternal immunologic tolerance in which the regulatory T lymphocytes (Tregs) play a crucial role. Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) is expressed transiently on activated T cells and constitutively on Tregs. CTLA-4 interacts with the B7 cell surface molec...