Reaction of oxabicyclic alkenes with alkynes and organoboronic acids in the presence of Ni(cod)(2), P(t-Bu)(3), and CsF in a binary solvent toluene-methanol (1 : 3) at 75 to 85 °C provided exo-5,6-disubstituted 7-oxanorbornene derivatives in good to excellent yields.

The synthesis of new 2,3,5,6-aryl substituted tetrahydro-2H-pyrazolo[3,4-d]- thiazoles 4a-j as potential biologically active compounds by the cyclocondensation of phenyl hydrazine with new 5-arylidene derivatives 2a-j of 2,3-disubstituted-1,3- thiazolidin-4-ones 1a-e is reported.

[reaction: see text] Enantio- and diastereoselective syntheses of trans-2,5-disubstituted morpholine derivatives are described. The routes are initiated by the reaction of enantiopure epoxides (2) with amino alcohols (3) and address the problem of regioselective hydroxyl activation-ring closure of the resulting amino diol adducts for (amino alcohol-derived) alkyl substituents of different steri...

The preparation, full characterization and determination of the absolute configuration of diastereomerically pure disulfoxide derivatives of Tröger's base are described. A sulfinyl-lithium exchange followed by the reaction with electrophiles affords synthetically meaningful amounts of enantiomerically pure 4,10-disubstituted Tröger's base analogues without any erosion of the stereogenic informa...

The straightforward enantioselective construction of the hydroquinoline ring system from 1,5-polycarbonyl derivatives, using (R)-phenyglycinol as a chiral latent form of ammonia, is reported. The process mimics the key steps believed to occur in nature in the biosynthesis of amphibian decahydroquinoline alkaloids. Diastereodivergent routes to enantiopure cis-2,5-disubstituted decahydroquinoline...

Imidazole and phenyl rings are fused at positions 4 5 to form the benzimidazole structure. The mono- disubstituted derivatives extremely intriguing heterocyclic chemical compounds. They can be synthesized using a straightforward condensation method between o-phenylenediamine carbonyl compound under various conditions as well nucleophilic substitution reaction. catalytical effects of derivatives...

One- and two-photon absorption cross-sections and spectra and the photophysical properties of eight perylenetetracarboxy-3,4:9,10-diimide (PDI) derivatives are reported and analyzed. The investigated compounds are characterized by direct binding of the phenyl rings of the substituents to the bay positions of the perylene core. They have been designed to test the effects of differences in the el...

Abstract The decarboxylative coupling of diversely substituted benzoic acids with internal alkynes proceeds smoothly in the presence a [RhCl(cod)]2/1,2,3,4-tetraphenyl-1,3-cyclopentadiene catalyst system to selectively produce highly naphthalene derivatives. is applicable constructing anthracene and benzo­[c]thiophene frameworks through reactions naphthoic thiophene-2-carboxylic acids, respecti...