Serial measurements of urinary adrenaline, noradrenaline, and 11-hydroxycorticosteroid excretion were performed on 32 healthy men under two conditions of work stress; piecework and work on assembly line. A statistically significant increase in adrenaline, noradrenaline, and 11-hydroxycorticosteroids was observed for piecework and assembly line workers compared with salaried and 'ordinary' worke...

Mutation of the functionally redundant Hoxa 11 Hoxd 11 genes gives absent or rudimentary kidneys resulting from a dramatic reduction of the growth and branching of the ureteric bud. To understand better the molecular mechanisms of Hoxa 11 Hoxd 11 function in kidney development, it is necessary to identify the downstream target genes regulated by their encoded transcription factors. To this end,...

Background and Aims: Avian infectious bronchitis virus (IBV) has a worldwide distribution and mutations occurring in the large viral genome of IBV have led to extensive antigenic variations among IBVs. This is the first study conducted to determine the complete membrane (M) gene sequences of different Iranian IBV genotypes. Materials and Methods: The M gene of three 793/B (IBKG1,6,7), one Mass...

C++ is the most commonly used language in introductory and intermediate programming courses in Bulgarian universities. In recent years this language has developed greatly. Its abstractions are more flexible and affordable than ever before. Such great number of changes are related to the launch of the new standard (known as C++11) that we have grounds to consider it even a new language. It is in...

the drb3 gene is a highly polymorphic major histocompatibility complex (mhc) class ii gene and plays an important role in variability of immune responsiveness and disease resistance. in the present study, the mhc class ii drb3 gene in water buffalo (bubalus bubalis) populations from northwest regions of iran was investigated through pcr-sscp. genomic dna was extracted from whole blood samples c...

Medullary thyroid cancer accounts for 5-10% of thyroid carcinomas. RET proto-oncogene mutations occur in all of the hereditary MTCs and about 66% of the sporadic MTCs. So, the detection of the RET mutations is necessary for rapid and proper diagnosis and treatment. This systematic review seeks to find a comprehensive list of RET gene mutations in the diagnosis of medullary thyroid cancer. The ...

The HDR syndrome is a rare autosomal dominant disorder characterised by Hypoparathyroidism, Deafness, and Renal dysplasia, caused inactivating heterozygous germline mutations in the GATA3 gene. We report an 11-year-old girl with mutation located at splice acceptor site of exon 5 gene (NM_001002295.2: c.925-1G>T). Functional studies using minigene assay showed that this abolished normal s...

background: acute myeloid leukaemia (aml) is a cancer of blood-forming cells in bone marrow. c-kit gene is a receptor tyrosine kinase class iii (rtk) that is expressed by early hematopoietic progenitor cells and plays an important role in hematopoietic stem cell proliferation, differentiation and survival. it is known that c-kit is a proto-oncogene and the activating c-kit mutations are likely ...