Alterations in the percent and absolute number of thymus-derived (T) and bursa-equivalent (B) lymphocytes in peripheral blood were followed in 10 patients treated with antithymocyte globulin, prednisone, and azathioprine after cardiac transplantation. During the 1st postoperative wk the percent of T cells dropped below 10% in almost all cases (normal range, 65-91%) with a concomitant rise in th...

Methods The data sources and methods of estimation used in this study are the same as those used for the 1988 calculations. Birth data were taken from publications of the NCHS,5 which obtains birth certificate information from state vital statistics agencies. The most recent NCHS data tabulate race according to the race of the mother rather than the child, and the NCHS has retabulated data from...

Background and objectives: Low social status increases risk of disease due, in part, to the psychosocial stress that accompanies feeling subordinate or poor. Previous studies report that chronic stress and chronically elevated cortisol can impair cardiovascular and immune function. We test whether lower status is more benign in small-scale, relatively egalitarian societies, where leaders lack c...

a Scientifi c Resource.—Bird collections were founded and built during the heyday of global exploration. The mission of these collections through most of their history has been to document avian diversity and its distribution and to serve as a resource for research and education. As bird collections became established and grew, ornithology itself became a scientifi c discipline and broadly expa...

In this article, the laser-based powder bed fusion (L-PBF) processing behavior of pure copper is evaluated by employing a conventional infrared fiber laser with wavelength 1080 nm, small focal spot diameter 37.5 µm, and power levels up to 500 W. It shown that bulk solid parts near full density (? Archimedes = 99.3 ± 0.2%, ? Optical 99.8 0.1%) can be produced using W for chosen combination parti...

OBJECTIVE To project the cost-effectiveness of fluconazole for prophylaxis against AIDS-related primary systemic fungal infections. DESIGN A Markov model with data from the literature. PATIENTS Hypothetical cohort of 100,000 AIDS patients. INTERVENTION No prophylaxis, and fluconazole prophylaxis beginning when a patient's CD4 count declined to below 200/mm3, below 100/mm3, or below 50/mm3...

Using an isoelectric-focusing (IEF) method developed to quantitate MM isoenzyme-creatine kinase (CK) sub-band activity, we identified a reproducible time-varying pattern of these sub-bands in the serum of eight patients with acute myocardial infarction (MI). Our observations are consistent with the view that MM3-CK (the M2-CK dimer, the pure gene product) is converted intravascularly to MM2-CK,...

microRNA-122 (miR-122) was one of the first examples of a tissue-specific miRNA. It is highly expressed in liver, where it constitutes 70% of the total miRNA pool. miR-122 expression is specific to the vertebrate lineage, where the sequence of the mature miRNA is completely conserved. miR-122 is a target for extensive study due to its association with cholesterol metabolism and hepatocellular c...

Here we describe lentivirus-infected cell microarrays for the high-throughput screening of gene function in mammalian cells. To create these arrays, we cultured mammalian cells on glass slides ‘printed’ with lentiviruses pseudotyped as vesicular stomatitis virus glycoprotein, which encode short hairpin RNA or cDNA. Cells that land on the printed ‘features’ become infected with lentivirus, creat...

The prevention of BBB breakdown and the subsequent vasogenic edema are important parts of the medical management of ischemic stroke. The purpose of this study was to investigate the ischemic tolerance effect of Rosmarinus officinalis leaf hydro-alcoholic extract (RHE).Five groups of animals were designed: sham (underwent surgery without MCAO) and MCAO groups, the MCAO groups were pretreated ora...