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Palmitoylation of the recombinant human A(1) adenosine receptor (A(1)AR) expressed in HEK-293 cells is demonstrated by showing that hexahistidine (His(6))/Asp-Tyr-Lys-Asp-Asp-Asp-Asp-Lys (FLAG) (H/F) A(1)ARs, purified to homogeneity from cells metabolically labelled with [(3)H]palmitate, incorporate tritium into a 38-42 kDa receptor glycoprotein. The amount of palmitoylation is not affected by ...
Received 11/26/2003; revised 12/18/2003; accepted 12/26/2003. For correspondence or reprints contact: Dong-Ling You, M.D., Department of Nuclear Medicine, Sun Yat-Sen Cancer Center, Koo Foundation, 125 Lih-Der Rd, Pei-tou District, Taipei 112, Taiwan. Tel: (886)2-28970011, Fax: (886)2-28971314, E-mail: [email protected] Background: Hepatocellular carcinoma (HCC) is a common cancer in Asia....
The aim of the evaluation was to establish bioequivalence between two oral 3.0 g sachet forms of L-ornithine-L-aspartate (LOLA). It was designed as randomised, two-way crossover study with a 1-week washout interval. Blood samples were collected throughout a 12 h period after administration of reference and test product to 12 fasting healthy male volunteers. Plasma were analyzed by sensitive, re...
Elevated C-terminal fibroblast growth factor 23 (C-FGF23) concentrations have been reported in Gambian children with and without putative Ca-deficiency rickets. The aims of this study were to investigate whether i) elevated C-FGF23 concentrations in Gambian children persist long term; ii) they are associated with higher intact FGF23 concentrations (I-FGF23), poor iron status and shorter 25-hydr...
BACKGROUND Pheochromocytoma is associated with catecholamine-induced cardiac toxicity, but the extent and nature of cardiac involvement in clinical cohorts is not well-characterized. OBJECTIVES This study characterized the cardiac phenotype in patients with pheochromocytoma using cardiac magnetic resonance (CMR). METHODS A total of 125 subjects were studied, including patients with newly di...
In 1993, the New York Public Service Commission approved a Niagara Mohawk subscription service offering which allows industrial and large commercial customers, who remain eligible for a shared savings program, to elect to be ineligible for rebate programs and to avoid being allocated some costs for the utility’s DSM resource programs. This decision was hailed by industrial customers who have be...
chattering region and successor states 4) (a) chatter{box algorithm ° . . . . . ↑ . . . . . ↑ . . . . . ↑ . . . . . ° INF A-1 0 T0 T1 T2 amount (B) ° . . . . . ↑ . . . . . ↑ . . . . . ↑ . . . . . ° INF A-2 0 T0 T1 T2 amount (C) ↑ . . . . . ↑↓ . . . . . ↓ . . . . . ↓ . . . . . ° INF 0 MINF T0 T1 T2 d amount (B) ° . . . . . ↑ . . . . . ° . . . . . ↓ . . . . . ° INF N-1 0 MINF T0 T1 T2 d amount (C...
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