Abstract Medulloblastomas (MB), the most common malignant pediatric brain tumor and a leading cause of childhood mortality, are stratified into four primary subgroups. Deletions within chromosomal locus 17p13.3, which houses multiple suppressor genes including miR-1253, characterize high-risk group 3 tumors. These aggressive tumors also enrich iron transport to satisfy their high proliferative ...

Objective Effective translation of evidence to practice may depend on systems of care characteristics within the health service. The present study evaluated associations between hospital expertise and infrastructure capacity and acute coronary syndrome (ACS) care as part of the SNAPSHOT ACS registry.Methods A survey collected hospital systems and process data and our analysis developed a score ...

We give new formulas for the asymptotics of the number of spanning trees of a large graph. A special case answers a question of McKay [Europ. J. Combin. 4 149–160] for regular graphs. The general answer involves a quantity for infinite graphs that we call ‘tree entropy’, which we show is a logarithm of a normalized determinant of the graph Laplacian for infinite graphs. Tree entropy is also exp...

OBJECTIVE The study focuses on psychosocial variables related to suicide ideation in young soldiers. METHOD 1329 Soldiers were randomly selected from the Infantry Forces in different regions. All the soldiers were requested to complete the Beck Scale for Suicide Ideation (BSSI) as well as General Health Questionnaire (GHQ-28). Data were analyzed using correlation tests. RESULTS The results ...

Bacillus subtilis was recently reported to synthesize unsaturated fatty acids (UFAs) with a double bond at positions 5, 7, and 9 (M. H. Weber, W. Klein, L. Muller, U. M. Niess, and M. A. Marahiel, Mol. Microbiol. 39:1321-1329, 2001). Since this finding would have considerable importance in the double-bond positional specificity displayed by the B. subtilis acyl lipid desaturase, we have attempt...