A linkage map of rye, previously developed using DS2 x RXL10 F2 mapping population, was enriched with 179 AFLP and 19 RAPD marker loci. The current map covers 1386 cM and contains 480 markers including 200 RFLPs, 179 AFLPs, 88 RAPDs, 12 protein loci and one dwarfing gene. AFLPs generated by EcoRI/MseI primer combinations were distributed over the entire genome as distinct loci or clusters of 2-...

Methotrexate and 6-mercaptopurine, important components of acute lymphoblastic leukemia treatment, are substrates for multidrug resistance-associated protein MRP4. Eight single nucleotide polymorphisms were analyzed in MRP4 gene, and 4 variants were identified as tagSNPs with frequency more than or equal to 5%. They were investigated for association with treatment responses in 275 children with...

1. Feldmann J, Prieur AM, Quartier P, et al. Chronic infantile neurological cutaneous and articular syndrome is caused by mutations in CIAS1, a gene highly expressed in polymorphonuclear cells and chondrocytes. Am J Hum Genet 2002;71:198-203. 2. Dollfus H, Hafner R, Hofmann HM, et al. Chronic infantile neurological cutaneous and articular/neonatal onset multisystem inflammatory disease syndrome...

[1] We estimated long‐term annual evapotranspiration (ETQ) at the watershed scale by combining continuous daily streamflow (Q) records, a simplified watershed water balance, and a nonlinear reservoir model. Our analysis used Q measured from 11 watersheds (area ranged from 12 to 1386 km) from the uppermost section of the Neuse River Basin in North Carolina, USA. In this area, forests and agricul...

Many methods have been developed based on extracting Local Binary Pattern features associating different classifying techniques in order to get more and more better effects of facial expression recognition. In this work, we propose a novel method for recognizing facial expressions based on Local Binary Pattern features and Support Vector Machine with two effective improvements. First is the pre...

TO THE EDITOR—Two systematic reviews and meta-analyses on the efficacy of tigecycline were performed and published in parallel [1–2]. They have reached similar conclusions, that overall mortality was increased in patients given tigecycline. This difference reached significance when all studies were included in our systematic review and meta-analysis [1]. In March 2012, Prasad et al [3] publishe...

These practice parameters have been developed by the American Academy of Child and Adolescent Psychiatry as a guide for clinicians evaluating psychiatric disorders in children and adolescents. The document focuses on the assessment, diagnostic, and treatment planning process, emphasizing a developmental perspective. The assessment process is intended for all children and adolescents presenting ...

Integrated quantum photonics relies critically on the purity, scalability, integrability, and flexibility of a photon source to support diverse quantum functionalities on a single chip. Here we report a chip-scale photon-pair source on the silicon-on-insulator platform that utilizes dramatic cavity-enhanced four-wave mixing in a high-Q silicon microdisk resonator. The device is able to produce ...