Early intervention by teams specialising in the treatment of early psychosis has been suggested to enhance outcome in the early phase of psychotic illness. Two papers in the Journal address this topic. The first examines the cost-effectiveness of these services, while the second examines the 5-year outcome of one such service. McCrone and colleagues (pp. 377–382) report that although their spec...

INTRODUCTION Removal of pulmonary secretions in mechanically ventilated patients usually requires suction with closed catheter systems or flexible bronchoscopes. Manual ventilation is occasionally performed during such procedures if clinicians suspect inadequate ventilation. Suctioning can also be performed with the ventilator entirely disconnected from the endotracheal tube (ETT). The aim of t...

Twenty two patients with gender dysphoria underwent neo-phalloplasties using a novel technique. Latissimus dorsi musculocutaneus re-innervated free flap was used to allow voluntary rigidity of the neo-penis. From the first 22 patients, 18 have obtained motoric function of reconstructed penis; the "paradox erection" was obtained. 14 patients came for examination after a follow-up period of mean ...

The system consists of more than 68,000 codes, compared to approximately 13,000 ICD-9-CM codes. ICD-10-CM codes have the potential to reveal more about quality of care, so that data can be used in a more meaningful way to better understand complications, better design clinically robust algorithms, and better track the outcomes of care. ICD-10-CM incorporates greater specificity and clinical det...

El cáncer de colon es una enfermedad frecuente que puede ser esporádica o familiar. La inactivación del gen supresor de tumores APC (adenomatous polyposis coli) se ha encontrado en más del 80% de los casos descritos de tumores colorrectales, apareciendo como una alteración temprana durante el desarrollo del pólipo adenomatoso. La inactivación del gen APC no es únicamente crítica en el proceso d...

Configuration management, the traditional CM, has been subsumed by a new CM, change management. The strategic organization looks ahead and this includes planning for change. This is an area of particular interest to software product line organizations. A product line organization must manage multiple options and control implementations of those options. In this issue of Strategic Software Engin...

OBJECTIVE To determine whether transthoracic three dimensional echocardiography is an accurate non-invasive technique for defining the morphology of atrial septal defects (ASD). METHODS In 34 patients with secundum ASD, mean (SD) age 20 (17) years (14 male, 20 female), the measurements obtained from three dimensional echocardiography were compared to those obtained from magnetic resonance ima...

Background: Congenital malformation (CM) is the major health problems in childhood because treatment and rehabilitation of children with CM is costly and complete recovery is usually impossible. For most of single primary defect the etiology is unknown. The aim of this study was to determine frequency of CM and its association with maternal age. Materials and Methods: This descriptive-observati...

Teenaged girls constitute the fastest growing segment of children and adolescents participating in organized athletics. Adolescent girls appear to have similar injury rates as boys in comparable activities but different injury patterns. To properly diagnose and manage athletic injuries in adolescent girls, pediatric health care providers must be aware of these differences, especially as the lit...