Background Rheumatoid Arthritis (RA) is a chronic inflammatory disease, which characterized by synovial inflammation resulting in bone and cartilage destruction. Crosstalk between activated fibroblast-like synoviocytes (FLS) immune cells, such as CD4 + T within the synovium might amplify joint Objectives To define interaction profile of FLS cells an setting to elucidate its consequence on infla...

Air concentrations of and inhalation exposure to total petroleum hydrocarbons (TPH) and benzene was monitored separately at two oil refineries from 1977 to 2014. Prevention policies and control measures that may explain changes were surveyed. The aim was to evaluate how the application of of Occupational Health and Safety Assessment Series OHSAS 18001.04 principles as well as Environmental prot...

reserve while still providing adequate funding to meet program expenses. This rule continues in effect the action that decreased the assessment obligation imposed on handlers. Assessments are applied uniformly on all handlers, and some of the costs may be passed on to producers. However, decreasing the assessment rate reduces the burden on handlers, and may reduce the burden on producers. In ad...

Background Rheumatoid arthritis (RA) is a chronic systemic inflammatory joint disease characterized by infiltration of the synovial membrane B cells, T and monocytes. Among most important extra-articular manifestations are those cardiovascular system. Cardiovascular involvement in this group patients highly relevant as it an cause morbidity mortality (1,2). Subclinical underestimated currently,...

Male black wheatears, Oenanthe leucura, carry on average almost 2 kg of stones to cavities inside caves before each clutch is laid. This costly behaviour may play a role in post-mating sexual selection, if females adjust their reproduction to the amount of stones carried by their mates, an hypothesis tested in two field experiments. First, breeding sites with many new stones also contained many...