CONTEXT Impaired mitochondrial function may influence processes highly dependent on energy, such as neurodevelopment, and contribute to autism. No studies have evaluated mitochondrial dysfunction and mitochondrial DNA (mtDNA) abnormalities in a well-defined population of children with autism. OBJECTIVE To evaluate mitochondrial defects in children with autism. DESIGN, SETTING, AND PATIENTS ...

Abū ‘Imrān Mūsā b. Abı̄ ’l-H ̇ ayy Khalı̄la. See (Abū ‘Imrān) Mūsā b. Abı̄ ’l-H ̇ ayy Khalı̄la Abū Ish ̇ āq Ibrahı̄m b. ‘At ̇ ā’, 2, 48, 180, 183 Abū ’l-Fad ̇ l b. Salmān, 315–317 Abū ’l-H ̇ asan b. H ̇ ayyim, 171, 293 Abūn b. S ̇ adaqa, 87, 128, 238, 294–295 Abū Sa‘ı̄d, 83, 131 agents and agency agency law, 130, 151–159, 358 agency transactions statistically compared, 143 as _ h _ ābunā and s _ uh _ ba comp...

A glutathione-S-transferase (GST)-C5a-green fluorescent protein (GFP) fusion protein was designed for use as a substrate for the streptococcal C5a peptidase (SCPA). The substrate was immobilized on a glutathione-Sepharose affinity matrix and used to measure wild-type SCPA activity in the range of 0.8 to 800 nM. The results of the assay demonstrated that SCPA is highly heat stable and has optima...

BACKGROUND AND PURPOSE Experimental studies suggested neurovascular compression of the brain stem as a cause of hypertension. The aim of our prospective study was to investigate the effect of microvascular decompression in patients with severe hypertension with neurovascular compression on blood pressure and central sympathetic nerve activity in the long-term. METHODS Fourteen patients (4 mal...

ArgRS (arginyl-tRNA synthetase) belongs to the class I aaRSs (aminoacyl-tRNA synthetases), though the majority of ArgRS species lack the canonical KMSK sequence characteristic of class I aaRSs. A DNA fragment of the ArgRS gene from Bacillus stearothermophilus was amplified using primers designed according to the conserved regions of known ArgRSs. Through analysis of the amplified DNA sequence a...