To understand the properties and/or reactivity of an organic molecule, an understanding of its three-dimensional structure is necessary. Simultaneous determination of configuration and conformation often poses a daunting challenge. Thus, the more information accessible for a given molecule, the better. Additionally to (3)J-couplings, two sources of information, quantitative NOE and more recentl...

Non-aqueous carbonate solvents have been the main choice for development of lithium-ion batteries, and similarly most research on sodium-ion batteries performed using carbonate-based solvents. However, differences between sodium lithium – in term chemistry/electrochemistry properties as well electrode materials used open up opportunities to a new look at that attracted little attention electrol...

Summary Intrinsically recyclable polymers represent a circular economy approach to address plastics problems. However, the design of such is challenged by unyielding trade-offs between monomer’s polymerizability and polymer’s depolymerizability performance properties. Here, we introduce hybrid monomer strategy that synergistically couples high ceiling temperature (HCT) sub-structure for propert...

Rhodococcus erythropolis is an environmental Gram-positive Actinobacterium with a versatile metabolism involved in various bioconversions and degradations. Rhodococci are best known for their great potential in numerous decontamination and industrial processes. However, they can also prevent plant disease by disrupting quorum sensing-based communication of Gram-negative soft-rot bacteria, by de...

Induction of apoptosis by tumor necrosis factor (TNF) is modulated by changes in the expression and activity of several cell cycle regulatory proteins. We examined the effects of TNF (1-100 ng/ml) and butyrolactone I (100 microM), a specific inhibitor of cyclin-dependent kinases (CDK) with high selectivity for CDK-1 and CDK-2, on three different cancer cell lines: WEHI, L929 and HeLa S3. Both c...