نتایج جستجو برای: 2 methylthio 1

تعداد نتایج: 3933856  

Journal: :The Journal of pharmacology and experimental therapeutics 1997
S S Greenberg J Ouyang X Zhao J Xie J F Wang T D Giles

Inducible nitric oxide synthase (iNOS) mRNA is up-regulated in vivo by dibutyryl-cAMP (db-cAMP), the purine-2y receptor agonist 2-methylthio-ATP and Escherichia coli endotoxin lipopolysaccharide (LPS). Ethanol and diethyldithiocarbamate inhibit LPS-stimulated iNOS mRNA. Their effects on db-cAMP- and 2-methylthio-ATP-stimulated iNOS mRNA remain undefined. We examined the effect of ethanol (4.5 g...

Journal: :Journal of bacteriology 1983
P van der Meijden H J Heythuysen H T Sliepenbeek F P Houwen C van der Drift G D Vogels

Methanol is converted to methane by crude extracts of Methanosarcina barkeri. The first reaction involved in this process, is catalyzed by methanol:2-mercaptoethanesulfonic acid methyltransferase (EC 2.1.1.-). The methyltransferase has an optimum at pH 6.5 and is not inhibited by 2-bromoethanesulfonic acid. Pyridoxal-5'-phosphate acts as an inhibitor (Ki = 0.30 mM). The methyltransferase was te...

2015
Amalia Z. Berna James S. McCarthy Rosalind X. Wang Kevin J. Saliba Florence G. Bravo Julie Cassells Benjamin Padovan Stephen C. Trowell

Currently, the majority of diagnoses of malaria rely on a combination of the patient's clinical presentation and the visualization of parasites on a stained blood film. Breath offers an attractive alternative to blood as the basis for simple, noninvasive diagnosis of infectious diseases. In this study, breath samples were collected from individuals during controlled malaria to determine whether...

Journal: :Molecular pharmacology 2002
David M Smith Aslamuzzaman Kazi Lisa Smith Timothy E Long Bart Heldreth Edward Turos Q Ping Dou

Many of the anticancer drugs in current use are toxic and thus limited in their efficacy. It therefore becomes essential to develop novel chemotherapeutic agents with lower levels of toxicity. The beta-lactam antibiotics have been used for many years to treat bacterial infections with limited or no toxicity. Until now, it has never been shown that beta-lactams could kill tumor cells. Here, for ...

Journal: :Zeitschrift für Kristallographie - New Crystal Structures 2014

Journal: :Zeitschrift für Kristallographie - New Crystal Structures 2014

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