A micro-method is described for the determination of trace amounts of D2O in serum, saliva and urine, requiring 100 microliters of sample. H2O/D2O are rapidly isolated from serum, saliva or urine by vacuum distillation. D2O concentrations in H2O are detected by infrared spectroscopy utilizing the integrated absorption of the OD-bond at 2510 cm-1 in the range of 2675 to 2460 cm-1. Calibration is...

Corrigiola telephiifolia Pourr. (Caryophyllaceae) is a Moroccan medicinal plant. Despite its popular usage, no study has been published concerning its toxicological profile. The acute toxicity of C. telephiifolia root extract was evaluated by giving it orally to mice at single doses of 5000, 10000, and 14000 mg/kg bodyweight. The extract was also administered at doses of 5, 70, and 2000 mg/kg b...

Although Lacosamide (LCM) has become a widely used drug in patients with status epilepticus, the role of LCM in patients with idiopathic generalized epilepsy presenting with absence status epilepticus (ASE) is currently unknown. A 57-year-old woman came to be under our observation after experiencing confusion and drowsiness, immediately after waking up. Her family history was unremarkable. Apar...

A laboratory trial was conducted to determine whether suspensions of ZnO nanoparticles (ZnO NPs) could interfere with the early growth of fenugreek. This plant species is one of the recommended species by Organization for Economic Cooperation and Development (OECD). Nine concentrations of ZnO NPs (10, 50, 100, 500, 1000, 2000, 3000, 4000, and 5000 mg/L) were prepared in deionized )DI( water (co...

Health practitioners all over the world have studied liver injury caused by drug side effects. Excessive production of free radicals causes cell damage, which has implications for pathological conditions in both humans and animals. Omega-3 fatty acids are a component fish that can work as hepatoprotective agents. Eel (Anguilla bicolor) is known to contain omega-3 including eicosapentaenoic acid...

Chemoprevention has become an important area in cancer research due to low success rate of current therapeutic modalities. Diet plays a vital role in the etiology of cancer. This research was carried out to study the chemopreventive properties of germinated rough rice (GRR) crude extract in Sprague-Dawley rats induced with azoxymethane. Germination of rough rice causes significant changes in se...

The application of legume green manure (LGM) is a traditional and valuable practice for agroecosystem management. In the present study, we conducted meta-analysis to explore effect LGM on yields three major grain crops in China under different cropping systems environmental conditions based 315 field trial datasets. increased yield significantly by 12.60% compared those no application, with whe...

Objectives: This study aimed to investigate the acute oral toxicity of 77 herbal formulas and performed in male female Sprague-Dawley (SD) rats as per guidelines mentioned Ministry Food Drug Safety.Methods: Each sex SD rat were administered a single dose (2000 or 5000 mg/kg) via gavage; control group received vehicle only. After administration, mortality, clinical signs, gross findings, body we...