BACKGROUND Fluoroquinolones are considered important substitutes for the treatment of tuberculosis. This study investigates the current status of fluoroquinolone for the treatment of tuberculosis. METHODS In 2009, a retrospective analysis was performed at one tertiary referral center for 953 patients diagnosed with tuberculosis. RESULTS A total of 226 patients (23.6%), who received fluoroqu...

Anath A Flugelman, et al. 259 Palliative medicine: a change in emphasis? Roderick MacLeod and Ann Nash 259 Double standards for screening Steve Iliffe 260 Screening elderly people P Fitton 260 The prevention of convulsions during benzodiazepine withdrawals R TA Scott 261 Characteristics of long-term benzo-diazepine users in general practice C J Hawley 261 The patient as consumer? Doreen Bugler ...

The enzyme thymidylate synthase (TS) catalyzes the reductive methylation of 2'-deoxyuridine 5'-monophosphate (dUMP) to 2'-deoxythymidine 5'-monophosphate. Using kinetic and X-ray crystallography experiments, we have examined the role of the highly conserved Tyr-261 in the catalytic mechanism of TS. While Tyr-261 is distant from the site of methyl transfer, mutants at this position show a marked...

The activity concentrations of 235U, 232Th, 226Ra, 40K and 137Cs in ground and surface of drinking water resources in Iranian city of Arak were determined by gamma ray spectrometry with aHPGe detector setup, coaxial p type and 8192 channels MCA. The water samples differed in radioactivity content depending on their origin and place. In the ...

Music therapy (MT) and music-based interventions (MBIs) are increasingly used for the treatment of substance use disorders (SUD). Previous reviews on the efficacy of MT emphasized the dearth of research evidence for this topic, although various positive effects were identified. Therefore, we conducted a systematic search on published articles examining effects of music, MT and MBIs and found 34...

INTRODUCTION The aim of this study was to determine the self-reported prevalence of stress, job satisfaction and burnout among radiation oncologists in Australia and New Zealand. A secondary aim was to determine the association between stress and satisfaction parameters with burnout. METHODS An anonymous online survey was distributed to all radiation oncologists listed on Royal Australian and...

edited by Reuven Dukas, University of Chicago Press, 1998. $95.00/£75.95 hbk, $30.00/£23.95 pbk (x+420 pages) ISBN 0 226 16932 4 (hbk), 0 226 16933 2 (pbk).