BACKGROUND The oxysterol 27-hydroxycholesterol (27-OHC) plays an important role in the regulation of cholesterol homeostasis. Pregnancy pathologies like preeclampsia (PE), HELLP-syndrome (HELLP), intrauterine growth restriction (IUGR) and intrahepatic cholestasis in pregnancy (ICP) are linked to disturbances in lipid metabolism. In the present study, we hypothesized a specific gestational regul...

OBJECTIVES The global increase in ESBL-producing Escherichia coli is associated with the ST131 clonal group, especially its CTX-M-15-producing H30Rx subset. To understand the rapid spread of ESBL-producing E. coli in Japan, we investigated the molecular epidemiology and ESBL-associated genetic environments of Japanese ST131 isolates. METHODS Between 2001 and 2012, 1079 ESBL-producing E. coli ...

......................................................................................................................... 7 ABBREVIATIONS ............................................................................................................. 9 LIST OF PUBLICATIONS.............................................................................................. 10 INTRODUCTION ...................

Two virtually superimposable mol-ecules comprise the asymmetric unit of the title compound, C(27)H(27)N(3). The range of dihedral angles between the central 1,3,5-triazine ring and the attached benzene rings is 20.88 (14)-31.36 (14)°, and the shape of each mol-ecule is of a flattened bowl. The crystal packing features weak C-H⋯π bonds and π-π inter-actions between triazine and benzene rings [ce...

Article history: Received 14 November 2008 Received in revised form 15 January 2012 Accepted 27 February 2012 Available online xxxx

11 Article history: 12 Received 19 November 2014 13 Accepted 27 June 2015 14 Available online xxxx 15

Article history: Received 14 October 2014 Received in revised form 27 October 2015 Accepted 21 November 2015 Available online xxxx