Perhaps the greatest barriers to achieving major public health advances in the 21st century will result from pandemic paradigm paralysis or the widespread inability to envision alternative or new models of thinking. One potential example of this phenomenon could turn out to be the continued focus on moderate and vigorous physical activity as the dominant health-related aspect of human movement....

BACKGROUND The World Health Organization (WHO) recommends Artemisinin-based Combination Therapy (ACT) for treating uncomplicated Plasmodium falciparum malaria. This review aims to assist the decision-making of malaria control programmes by providing an overview of the relative effects of dihydroartemisinin-piperaquine (DHA-P) versus other recommended ACTs. OBJECTIVES To evaluate the effective...

First-degree relatives of people with type 2 diabetes are themselves at risk of developing the disease. While the transmission of genetic information from parents to offspring contributes to diabetes risk, there are other nongenetic risk factors that are shared by family members that can be amenable to intervention. These factors are likely to include sedentary behaviors such as television view...

In this work, we report the optical properties of Tm ions in tellurite glasses (TeO2-TiO2-Nb2O5) for different Tm 3+ concentrations ranging between 0.05 and 1 wt%. Judd-Ofelt intensity parameters have been determined to calculate the radiative transition probabilities and radiative lifetimes of excited states. The stimulated emission cross-sections of the infrared emissions at 1487 nm and 1800 ...

3 nerve growth factor (NGF), a targetderived protein necessary for survival and development of sympathetic and sensory neurons, can also affect subpopulations of neurons in the central nervous system (CNS). Using a blot hybridization assay capable of detecting 10 fg of mRNA, we measured the levels of NGF mRNA in the major brain regions, including those innervated by NGF-responsive neurons. NGF ...

HomeCirculation: Cardiovascular InterventionsVol. 14, No. 4The Art of Prescribing β-Blockers After Myocardial Infarction Free AccessEditorialPDF/EPUBAboutView PDFView EPUBSections ToolsAdd to favoritesDownload citationsTrack citationsPermissions ShareShare onFacebookTwitterLinked InMendeleyRedditDiggEmail Jump toFree AccessEditorialPDF/EPUBThe Liyew Desta, MD, PhD, Sergio Raposeiras-Roubin, PhD...

Epidemic thunderstorm asthma (ETSA) is a global health problem that can strike without sufficient warning and have catastrophic consequences. Because of climate change, future events are likely to become more common, disastrous, unpredictable. To prevent loss life avoid surge on care infrastructure, identifying at-risk individuals their potential biomarkers the most prophylactic approach be tak...

•Synaptic vesicles coat active zone condensate but coacervate with synapsin condensate•SV/synapsin co-condensates encapsulate SV-coated condensates•A presynaptic bouton-like assembly reserve and tethered SV pools is reconstituted•Membraneless condensates membrane organelles can interact distinct modes Tethering of synaptic (SVs) to the determines strength, although molecular basis governing tet...

•Capping curtailment increases costs and emissions jeopardizes reliability•Capping reduces renewable capacity flexible resource capacity•Capping fossil fuel utilization hydro utilization•Policymakers must think carefully about the unintended effects of caps As countries pursue power system decarbonization, a well-intentioned strategy being pursued in jurisdictions like China is strict integrati...

The 351-nm photoelectron spectrum of the negative ion of 1,3-benzoquinodimethane (m-xylylene) is reported. Features are observed in the photoelectron spectrum corresponding to formation of the B2, A1, and B2 states of m-xylylene. The electron affinity of the triplet ground state is found to be 0.919 ( 0.008 eV, and vibrational frequencies of 290, 540, and 1500 cm-1 are obtained. The active mode...