Precise removal of introns from metazoan precursor mRNAs is critical for gene expression. Nevertheless, alternative splicing provides a means for higher eukaryotes to increase genomic complexity and proteome diversity and to regulate certain cellular functions. The presence of rare U12-type pre-mRNA introns in eukaryotic genomes further complicates splicing events. In this review, we discuss th...

limit and discard others for statistical reasons.) A least squares solution of these equations will determine the three unknowns u12, u22 and u32. In forming the normal equations the number of stars in each region should enter as the weight factor. This short note was inspired by Professor S. Chandrasekhar's stimulating colloquium on the paper cited previously; thus I should like to express my ...

Isotope shifts in dielectronic recombination spectra were studied for Li-like (A)Nd(57+) ions with A=142 and A=150. From the displacement of resonance positions energy shifts deltaE(142 150)(2s-2p(1/2))=40.2(3)(6) meV [(stat)(sys)] and deltaE(142 150)(2s-2p(3/2))=42.3(12)(20) meV of 2s-2p(j) transitions were deduced. An evaluation of these values within a full QED treatment yields a change in t...

Completely fine-structure-resolved photoelectron spectra produced from sodium atoms selectively excited into the Na* 2p(6)3p (2)P(1/2) and (2)P(3/2) states were obtained using a third generation synchrotron source in conjunction with laser pumping and high-resolution spectrometry. The spectra show dramatically different behaviors. The strong variations observed in the regions of the Na+ 2p(5)3p...

A block code of the form (2p)B(2p+1)B cannot provide both d.c. balance and redundant codewords for control signals. We describe a new set of additional rules that may be applied to groups of consecutive codewords in order to provide both d.c. balance and a large control space, and show how 256 10-bit control symbols may be achieved with a d.c. balanced 4B5B code. Introduction: nBmB block coding...

background : this study was set to determine the optimal technique of breast cancer with supraclavicular fossa irradiation. methods : three techniques was compared in this study. techniques were two point symmetric (2p-sym), two point asymmetric (2p-asym) and single point (sp). in 2p-sym all of beams were symmetric, in 2p-asym tangential beams were symmetric and supra was asymmetric, in sp all ...

BACKGROUND Postmastectomy radiotherapy was shown in previous meta-analyses to reduce the risks of both recurrence and breast cancer mortality in all women with node-positive disease considered together. However, the benefit in women with only one to three positive lymph nodes is uncertain. We aimed to assess the effect of radiotherapy in these women after mastectomy and axillary dissection. M...

Nowadays, with the increasing number of integrated data sources, there is a real trend to personalize mediation systems to improve user satisfaction. To make these systems user sensitive, we propose a personalization platform called 2P-Med. 2P-Med allows personalizing any mediation system used in any domain following a cyclic process. The process includes building and managing adequate user pro...

We develop the formalism based on the S-matrix for 3 → 3 scattering to derive the direct three-body resonant radiative capture reaction rate. Within this formalism the states, which decay only/predominantly directly into three-body continuum, should also be included in the capture rate calculations. Basing on the derivation, as well as on the modern experimental data and theoretical calculation...