Context. Only two planetary systems around old ms-pulsars are currently known. Young radio pulsars and radio-quiet neutron stars cannot be covered by the usually-applied radio pulse timing technique. However, finding substellar companions around these neutron stars would be of great interest – not only because of the companion’s possible exotic formation but also due to the potential access to ...

Derivatives of the Edmonston-B strain of measles virus (MV-Ed) are safe, live attenuated measles virus (MV) vaccines that have been used worldwide for more than 30 years. The cytoreductive potential of MV-Ed has been investigated in murine models of both aggressive and indolent B-cell lymphoma in severe combined immunodeficient (SCID) mice. The rationale for these studies was generated by exper...

AIMS Growth factors play an important role in regulating vascular function. Data are limited regarding clinical and genetic correlates of endothelial growth factors and their associations with vascular function. METHODS AND RESULTS We evaluated clinical and genetic correlates of circulating vascular endothelial growth factor A (VEGF), its soluble receptor sFlt-1, and hepatocyte growth factor ...

Abstract Background Several drugs are being repurposed for the treatment of coronavirus disease 2019 (COVID-19) pandemic based on in vitro or early clinical findings. As these used varied regimens and dosages, it is important to enable synthesis existing safety data from trials. However, availability information limited by a lack timely reporting overall trial results public registries through ...

During the last couple of years astronomers and astrophysicists have been debating on the fact whether the so called ‘strange stars’ stars made up of strange quark matter, have been discovered with the candidates like SAX J1808.4−3658, 4U 1728−34, RX J1856.5−3754, etc. The main contention has been the estimation of radius of the star for an assumed mass of ∼ 1.4M⊙ and to see whether the point o...

OBJECTIVE Previous studies have identified differential item function (DIF) in depressive symptoms measures, but the impact of DIF has been rarely reported. Given the critical importance of depressive symptoms assessment among older adults, we examined whether DIF due to demographic characteristics resulted in salient score changes in commonly used measures. METHODS Four longitudinal studies ...

We present limits to the log N − log S curve for isolated neutron stars, both cooling and accreting neutron stars, which are not active as radio pulsars, as observed with the ROSAT All-Sky Survey and compare it with theoretical expectations. So far, only one isolated neutron star is identified optically among ROSAT sources, namely RXJ185635-3754 (Walter & Matthews 1997). Three more promising ca...

Cooling of neutron stars (NSs) with the cores composed of neutrons, protons, and electrons is simulated assuming S0 pairing of neutrons in the NS crust, and also S0 pairing of protons and weak P2 pairing of neutrons in the NS core, and using realistic density profiles of the superfluid critical temperatures Tc(ρ). The theoretical cooling models of isolated middle-aged NSs can be divided into th...

We cloned a 4414-bp element from a mutant of Drosophila melanogaster. Its insertion site was 18,929,626 bp. Analysis of the nucleotide and amino acid sequences demonstrated that the element is homologous to Pifo_I, first obtained from D. yabuka, which belongs to the gypsy/Ty3 subfamily. We also obtained a 3754-bp length element from a wild-type fly by PCR, with a pair of primers designed from t...

BACKGROUND The dissemination and use of automated external defibrillators (AEDs) beyond traditional emergency medical services (EMS) into the community has not been fully evaluated. We evaluated the frequency and outcome of non-EMS AED use in a community experience. METHODS AND RESULTS The investigation was a cohort study of out-of-hospital cardiac arrest cases due to underlying heart disease...