A 32-year-old man was admitted in the Emergency Department with acute dyspnea secondary to spontaneous pneumothorax. He had history of spontaneous pneumothorax 2 years ago.He was active cigarette smoker (10 pack/year). The family history was unremarkable for lung diseases. Additionally, he had no systemic complaints.The lung HRCT revealed multiple bizarre-shaped cysts distributed in both lungs ...

1. The breakdown and faecal bulking capacity of dietary fibre preparations from wheat bran, apple, cabbage, carrot, and guar gum were compared in man and rat. 2. The degradation of the fibre showed good correlation between man and rat (r 0.99, regression coefficient 0.86). Wheat bran was the least well-digested, 66 and 59% of the neutral sugars being excreted in faeces of man and rat respective...

About 1% of the human proteome is anchored to the outer leaflet of cell membranes via a class of glycolipids called GPI anchors. In spite of their ubiquity, experimental information about the conformational dynamics of these glycolipids is rather limited. Here, we use a variety of computer simulation techniques to elucidate the conformational flexibility of the Man-α(1→2)-Man-α(1→6)-Man-α(1→4)-...

Abstract The Book of Job treats the Problem Evil. It is divided into two documents: (1) framework story, that is, Prologue and Epilogue (Job 1:1–2:13; 42:7–17); (2) speeches by Job, his friends, God. In presented as a just man who serves God in good times bad 1:21; 2:10). speeches, accused ‘destroying hope man’ 14:19). replies with an ad hominem argument: ‘Where were you when I laid foundation ...

Section 1 establishes some key similarities between Heidegger and Georg Simmel in order to motivate the hypothesis that Simmel’s account of how society is possible can be used to give an account of das Man which reconciles the transcendentally philosophical role emphasised by Dreyfus with the ethically negative features emphasised by Olafson. Section 2 elaborates the issue addressed in Ch. 4 of...

A previous study (vijay, I. K., Perdew, G. H., and Lewis, D. E. (1980) J. BioL Chem. 255, 11210-11220) indicated that incubation of a membrane preparation from the lactating bovine mammary tissue with UDPISH]GlcNAc and GDP-[’“C]Man synthesized a series of lipid-linked saccharides that appeared to be related to one another as precursor products in the biosynthesis of asparagine-linked glycoprote...

4(5)-(3,3-Dimethyl-l-triazeno) imidazole-5(4)-carboxamide (DIC, NSC 45388) was administered i.v. to 15 patients with malignant melanoma and to 17 patients with other tumors at a dosage of 4.5 mg/kg/day for 10 days. In the melanoma group, 5 patients responded to therapy. No responses were seen in the 17 patients with other tumors. Toxicity was manifested-by nausea and vomiting, leukopenia, and t...

Experimental neurochemical provocation of panic attacks in susceptible human subjects has considerably expanded our knowledge of the pathophysiology and psychopharmacology of panic disorder. Some panicogens also elicit short-lived panic-like states in healthy man. This offers the opportunity to assess the anti-panic action of drugs in proof-of-concept studies. However, from current data it is s...