Background: Physicians and geneticists face challenges in making accurate diagnoses during clinical evaluations; affecting patients clinicians. The aim of this study was to estimate the hit rate non-consanguineous population. Moreover, prevalence genetic disorder both consanguineous non- population Saudi Arabia at King Abdulaziz Medical City Riyadh data. Methods: We reviewed 681 families 1563 i...

Office workers generally have low physical activity, causing a lack of burning energy by the body. Energy in body will be stored fat and cause amount deposits is not reduced as well an increase glucose blood. Eventually experience weight blood sugar levels. Lifestyle like this at risk for diabetes mellitus. Efforts controlling levels (KGD) are effective only done with treatment, therefore preve...

Fluid-driven fracture propagation is widely observed in various geological processes and crucial to many applications of engineering. Developing robust accurate numerical strategies has significance advancing the scientific understanding engineering related with fluid-driven propagation. We present a finite element-finite volume strategy using asymptotic tip enrichment model three-dimensional C...

INTRODUCTION The purpose of this study was to assess the requirement for the RGD sequence of von Willebrand factor (VWF) for its binding to the beta3 chain of integrins and the structural basis for the specificity of monoclonal antibody (MoAb) 9 which specifically binds to VWF and inhibits this interaction. MATERIAL AND METHODS : Seven point mutations were introduced into VWF by site-directed...

Anti-Stokes fluorescence can be used to cool a material if its radiative quantum efficiency is nearly unity. Until recently, the only solid which had shown net cooling was an ytterbium-doped heavy metal fluoride glass. Reasons for the lack of success with other materials include energy transfer to unwanted impurities, trapping of the fluorescence by internal reflection and reabsorption, and non...

This research was conducted to examine the drinking (WQI1) and irrigation (WQI2) water quality for Bhavani river basin using statistical methodologies. The study area geographically covers up 4207 km2. For evaluating Water Quality Index (WQI), fourteen groundwater parameters were employed data gathered two decades (1972–1990 & 2010–2019). include TDS, pH, EC, TH, Ca2+, Mg2+, Na+, K+, CO3 2-...

A new ab initio pair potential for water was generated by fitting 2510 interaction energies computed by the use of symmetry-adapted perturbation theory ~SAPT!. The new site–site functional form, named SAPT-5s, is simple enough to be applied in molecular simulations of condensed phases and at the same time reproduces the computed points with accuracy exceeding that of the elaborate SAPT-pp funct...

BACKGROUND Social inequalities in mental disorders have been described, but studies that explain these inequalities are lacking, especially those using diagnostic interviews. This study investigates the contribution of various explanatory factors to the association between educational level and major depression and generalised anxiety disorder in Irish men and women. METHODS The study populat...