The results of the Focus Simplexa FluA/B & RSV Direct assay were compared to those of laboratory-developed reverse transcription PCR tests for 498 nasopharyngeal swabs. Concordance rates were 96.6% (476/493; κ = 0.91), 97.6% (481/493; κ = 0.47), and 99.2% (488/492; κ = 0.94) for influenza A, influenza B, and respiratory syncytial virus, respectively.

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We report the construction of a corpus for parser evaluation in the biomedical domain. A 50-abstract subset (492 sentences) of the GENIA corpus (Kim et al., 2003) is annotated with labeled head-dependent relations using the grammatical relations (GR) evaluation scheme (Carroll et al., 1998) ,which has been used for parser evaluation in the newswire domain.

Ca(2+)-Calmodulin binding to the variable N-terminal region of the diacylglycerol/phorbol ester-binding UNC13/Munc13 family of proteins modulates the short-term synaptic plasticity characteristics in neurons. Here, we report the sequential backbone and side chain resonance assignment of the Ca(2+)-Calmodulin/Munc13-1(458-492) peptide complex at pH 6.8 and 35 degrees C (BMRB No. 15470).

The peptide domain of salivary agglutinin responsible for its interaction with cell surface protein antigen (PAc) of Streptococcus mutans or bovine lactoferrin was found in the same peptide, scavenger receptor cysteine-rich domain peptide 2 (SRCRP2). Inhibition studies suggest that PAc and lactoferrin, of which residues 480 to 492 seem important, competitively bind to the SRCRP2 domain of saliv...

M.R.C.G.P............. ................... 485 axThalassaemia in Britain J. L. Raven, F.R.C.P.A. and Jennifer A. Tooze, A.I.M.L.T ......................... 486 Clinical Diagnostic Process: An Analysis F. M. Hull, M.R.C.G.P ................... 486 Brachial Plexus Palsy after Parenteral Feeding M. J. Whittle, M.B ................ 486 Health as a Quantifiable Property J. R. Audy, M.D ................

479-492 and 1 : 100 against GABA, receptor purified from adult bovine'cerebral cortex. The titre is defined as that dilution of serum which would produce an absorbance equal to half of the maximum response. The immune response against purified GABA, receptor, measured by ELISA was blocked by preincubating the serum with the free Cys-a3 479-492 peptide (Fig. la) . A Western blot of purified GABA...

It has been shown previously that glutaraldehyde cross-links the Ca(2+)-ATPase of sarcoplasmic reticulum intramolecularly at the active site, involving residues participating in nucleotide binding and the conformational change that results in Ca2+ release to the vesicle lumen and formation of ADP-insensitive E2-P (Ross, D. C., Davidson, G. A., and McIntosh, D. B. (1991) J. Biol. Chem. 266, 4613...

Two glycoforms of a secretable human thrombomodulin mutant [TMD1-105 and TMD1-75; Parkinson, Grinnell, Moore, Hoskins, Vlahos & Bang (1990) J. Biol. Chem. 265, 12602-12610] were expressed in human 293 cells and used to study the role of glycosylation in the functions of this endothelial-cell thrombin receptor. Carbohydrate content analysis and intrinsic labelling with [3H]glucosamine and [35S]s...