Article history: Received on: 25/09/2013 Revised on: 02/11/2013 Accepted on: 25/11/2013 Available online:29/11/2013 The present study was carried out to assess the effect of plant's extract on Ehrlich ascites carcinoma (EAC) and its influence on redox status and tissue injury on liver. Among five groups of albino mice, three were treated with plant's extract, in addition, a group treated with t...

as: Hama e Associa Abstract This study was designed to evaluate effect of trigonelline and ethanol extract of Iraqi Fenugreek seeds on oxidative stress in alloxan diabetic rabbits. Oral dose of (10 mg/12 h) isolated trigonelline or (7.7 ml/12 h) of ethanol extract of Iraqi Fenugreek seeds was administered to the rabbits for four weeks. Plasma malondialdehyde (MDA) and glutathione (GSH), as oxid...

Background: Some health-protecting secondary metabolites can be found at a higher concentration in the sprouts compared to other stages of plant growth. In addition, environmental stresses such as salt stress may be resulting in the increase or decrease of specific secondary metabolites in sprouts and plants. Objective: Evaluation the changes of trigonelline, nicotinic acid, and proline cont...

OBJECTIVE Diabetes mellitus is a group of metabolic diseases characterized by chronic hyperglycemia condition resulting from defective insulin secretion or resistance insulin action, or both. The purpose of this study was to evaluate the effect of 6 weeks swimming training and Trigonella foenum-graecum seed (fenugreek) extract, alone and in combination, on plasma glucose and cardiac antioxidant...

BACKGROUND Having considered how bioavailable aluminium (Al) may affect ecological systems and animals living there, especially cattle, and in search for a preventive dietary treatment against Al toxicity, we aimed to test the protective role of fenugreek seeds against chronic liver injury induced by aluminum chloride (AlCl3) in Wistar rats. RESULTS Five months of AlCl3 oral exposure (500 mg/...

BACKGROUND & OBJECTIVES Trigonella foenum graecum commonly known as fenugreek, has been widely cultivated in Asia, Africa and Mediterranean countries for the edible and medicinal values of its seeds. Earlier reports show that fenugreek seeds provide a mastogenic effect resulting in enhanced breast size. However, very little is known about its estrogenic effect. The present study investigated th...

In the present study, investigations were carried out to screen the anticancer activities of fenugreek seed oil against cancer cell lines (HEp-2, MCF-7, WISH cells), and a normal cell line (Vero cells). Cytotoxicity was assessed with MTT and NRU assays, and cellular morphological alterations were studied using phase contrast light microscopy. All cells were exposed toi 10-1000 μg/ml of fenugree...

Protein and DNA polymorphismswere surveyed among seven accessions of wild fenugreek (Trigonellafoenum-graecum L.) to estimate their genetic diversity and relationships. Samples were obtained from diverse ecogeographical areas in Saudi Arabia and Yemen. Sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) analysis of seed storage protein showed genetic variations among fenugreek ...

Alzheimer's disease (AD) is the most common form of dementia that mainly affects the cognitive functions of the aged populations. Trigonella foenum-graecum (L.) (fenugreek), a traditionally well utilized medicinal plant ubiquitously used as one of the main food additive worldwide, is known to have numerous beneficial health effects. Fenugreek seed extract could be able to inhibit the activity o...

Background Effective interventions on exclusive breastfeeding that are appropriate for the existing conditions can have significant benefits on maintenance, continuity, and promotion of breastfeeding in mothers. The aim of this study is to evaluate the effect of Fenugreek on breast milk sufficiency in nursing mothers. Materials and Methods<...