نتایج جستجو برای: 68ga citrate

تعداد نتایج: 16735  

2016
Duygu Has Şimşek Serkan Kuyumcu Bilge Bilgiç Emine Göknur Işık Cüneyt Türkmen Işık Adalet

A 54-year-old woman with suspicion of neuroendocrine tumor (NET) was referred for 68Ga-DOTATATE positron emission tomography/computed tomography (CT) imaging due to clinical findings. A well-defined osteolytic lesion on the corpus of the third lumbar vertebra was evident on CT images with mild uptake of 68Ga-DOTATATE, which led to suspicion of NET metastasis. Histopathologic examination reveale...

Journal: :Indian Journal of Medical and Paediatric Oncology 2023

Abstract We in this article have presented a review of the guideline recommendations on theranostic positron emission tomography-computed tomography (PET-CT) imaging which will be helpful to assist practitioners providing appropriate patient care. Multiple guidelines by different societies and medical associations provide standards for diagnosis, imaging, treatment cancer patients. They generat...

2017
Bart de Keizer Gerard C. Krijger F. Tessa Ververs Robert J. J. van Es Remco de Bree Stefan Willems

A patient with a history of adenoid cystic carcinoma of the nasal cavity presented himself with bone pain and an elevated PSA level. On suspicion of metastatic prostate cancer a 68Ga-PSMA PET-CT was performed. The PET-CT showed numerous lung and non-sclerotic bone metastasis. Biopsy of a bone metastasis was performed and pathology showed adenoid cystic carcinoma instead of prostate cancer. Immu...

Journal: :Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2007
Orazio Schillaci

In this issue of The Journal of Nuclear Medicine, Gabriel et al. (1) report their experience with 68Ga-labeled 1,4,7,10tetraazacyclododecane-N,N9,N99,N999tetraacetic acid-D-Phe1-Tyr3-octreotide (68Ga-DOTA-TOC) PET in a series of 84 patients with neuroendocrine tumors (NET). PET was more accurate with a higher detection rate than somatostatin receptor scintigraphy (using 111In-DOTA-TOC or 99mTc-...

2014
Simone Maschauer Tina Ruckdeschel Philipp Tripal Roland Haubner Jürgen Einsiedel Harald Hübner Peter Gmeiner Torsten Kuwert Olaf Prante

The neurotensin receptor (NTS1) has emerged as an interesting target for molecular imaging and radiotherapy of NTS-positive tumors due to the overexpression in a range of tumors. The aim of this study was to develop a 177Lu-labeled NTS1 radioligand, its application for radiotherapy in a preclinical model and the imaging of therapy success by small-animal positron emission tomography (µPET) usin...

Journal: :Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2017
Fabien Hyafil Jaroslav Pelisek Iina Laitinen Margret Schottelius Miriam Mohring Yvonne Döring Emiel P C van der Vorst Michael Kallmayer Katja Steiger Andreas Poschenrieder Johannes Notni Johannes Fischer Christine Baumgartner Christoph Rischpler Stephan G Nekolla Christian Weber Hans-Henning Eckstein Hans-Jürgen Wester Markus Schwaiger

68Ga-pentixafor is a radiotracer for PET that binds with nanomolar affinity to CXCR4. The CXCR4 receptor is expressed at the surface of inflammatory cells. The objective of the study was to analyze the ability of radiolabeled pentixafor to detect CXCR4 expression on inflammatory cells present in atherosclerotic plaques of an experimental rabbit model. Methods: Atherosclerotic plaques were induc...

2017
Annika Herlemann Alexander Kretschmer Alexander Buchner Alexander Karl Stefan Tritschler Lina El-Malazi Wolfgang P. Fendler Vera Wenter Harun Ilhan Peter Bartenstein Christian G. Stief Christian Gratzke

The management of patients with biochemical recurrence (BCR) after definitive treatment for prostate cancer remains controversial. Our aim was to determine survival rates and complications of salvage lymph node dissection (sLND) in patients with recurrent prostate cancer after radical prostatectomy, while evaluating biochemical response (BR) with two different positron emission tomography/compu...

2011
Elise M. Blanchet Victoria Martucci Karel Pacak

Paragangliomas are neural crest-derived tumors, arising either from chromaffin sympathetic tissue (in adrenal, abdominal, intra-pelvic, or thoracic paraganglia) or from parasympathetic tissue (in head and neck paraganglia). They have a specific cellular metabolism, with the ability to synthesize, store, and secrete catecholamines (although most head and neck paragangliomas do not secrete any ca...

2017
Sebastian Meißner Jan-Carlo Janssen Vikas Prasad Winfried Brenner Gerd Diederichs Bernd Hamm Frank Hofheinz Marcus R. Makowski

BACKGROUND The aim of this study was to evaluate the diagnostic value of the asphericity (ASP) as a novel quantitative parameter, reflecting the spatial heterogeneity of tracer uptake, in the staging process of patients with 68Ga-PSMA-HBED-CC positron emission tomography (PET)-positive prostate cancer (PC). In this study, 37 patients (median age 72 years, range 52-82 years) with newly diagnosed...

2017
Silvano Gnesin Periklis Mitsakis Francesco Cicone Emmanuel Deshayes Vincent Dunet Augusto F Gallino Marek Kosinski Sébastien Baechler Franz Buchegger David Viertl John O Prior

BACKGROUND Integrin-targeting radiopharmaceuticals have potential broad applications, spanning from cancer theranostics to cardiovascular diseases. We have previously reported preclinical dosimetry results of 68Ga-NODAGA-RGDyK in mice. This study presents the first human dosimetry of 68Ga-NODAGA-RGDyK in the five consecutive patients included in a clinical imaging protocol of carotid atheroscle...

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