α-Tocopherol (vitamin E) has attracted considerable attention as a potential protective or palliative agent. In vitro, its free radical-scavenging antioxidant action has been widely demonstrated. In vivo, however, vitamin E treatment exhibits negligible benefits against oxidative stress. α-Tocopherol influences lipid ordering within biological membranes and its derivatives have been suggested t...

We wanted to determine whether alpha-tocopherol supplementation to pregnant rats could increase the concentration of alpha-tocopherol in maternal and fetal plasma and tissues. Pregnant rats were treated with alpha-tocopherol on days 18 and 19 gestation and studied at day 20. A control group was studied in parallel. Treatment of pregnant rats with alpha-tocopherol increased its concentration in ...

The aim of this study was to determine the chemical composition (fatty acids, tocopherols, and sterols) evaluate oxidative stability Moroccan pomegranate ( Punica granatum L.) seed oil. oil content 22.63 g/100g dry weight. fatty acid showed a dominance conjugated linolenic acids (CLnAs) (86.96 g/100g). most dominant punicic (75.1 g/100g), followed by catalpic (6.7 g/100g) linoleic with amounts ...

Diabetes and hypertension are closely associated with impaired endothelial function. Studies have demonstrated that regular consumption of edible palm oil may reverse endothelial dysfunction. The present study investigates the effect of palm oil fractions: tocotrienol rich fraction (TRF), alpha-tocopherol and refined palm olein (vitamin E-free fraction) on the vascular relaxation responses in t...

BACKGROUND Contrast-induced acute kidney injury (CI- AKI) increases the likelihood of patient morbidity and mortality following coronary procedures. Volume supplement with saline is the standard treatment to prevent CI-AKI. Additional antioxidant prophylaxis has often yielded conflicting results. The present study was conducted to examine the role of novel application vitamin E (tocopherol) in ...

The phytosterol and tocopherol contents of almond kernel oil were evaluated in three cultivars, including the Spanish cultivar ‘Marcona’ French cultivars ‘Ferragnès’ ‘Ferraduel’, grown under two different agro-climatic conditions, Zaragoza (Spain) Meknès (Morocco). analysis variance showed significant effects genotype on content, Δ5-Avenasterol, Δ7-Campesterol, Stigmasterol isomers. location ef...

In this study, waste edible oil was prepared by both heat and aeration treatment, and the increasing inhibitive effect of tocopherol treatment on the acid value (AV) and carbonyl value (CV) of the oil was investigated. The AV and CV of waste edible oil treated with tocopherol were 0.1-1.0% lower than those of the nontreated oil, indicating that tocopherol exerted a radical-scavenging activity. ...

A relatively rapid procedure is described for the spectrophotometric determination of total tocopherol in red blood cells (RBC) based on a modification of the original Emmerie-Engel reaction. The critical feature in this method is the presence of a large amount of an added antioxidant, pyrogallol or ascorbic acid, during the saponification and extraction stages and the use of thin-layer chromat...

The plasma tocopherol level is often low in cirrhosis (1, 2). Whether such low values reflect alterations in the absorption, utilization or excretion of tocopherol related to liver damage, or are the result of a decreased dietary intake is not known. Previous attempts to investigate tocopherol metabolism in liver disease have been limited to tests of tocopherol tolerance based on plasma curves ...

BACKGROUND Vitamin E supplementation has been recommended for persons with familial hypobetalipoproteinemia (FHBL), a rare disorder of lipoprotein metabolism that leads to low serum alpha-tocopherol and decreased LDL-cholesterol and apolipoprotein (apo) B. We examined the effect of truncated apoB variants on vitamin E metabolism and oxidative stress in persons with FHBL. METHODS We studied 9 ...