نتایج جستجو برای: a26
تعداد نتایج: 136 فیلتر نتایج به سال:
Behçet disease (BD) is a multisystem autoinflammatory condition characterized by mucosal ulceration and predominantly neutropilic inflammation of immune privileged sites including the eye, brain, and synovial joint (1). In PNAS, Ombrello et al. analyze a combination of directly ascertained and imputated single nucleotide polymorphisms (SNPs) in the HLA-B region in Turkish patients with BD (2). ...
The human major histocompatibility complex (MHC) on chromosome 6p21 is a paradigm for genomics, showing remarkable polymorphism and striking association with immune and non-immune diseases. The complex genomic landscape of the MHC, notably strong linkage disequilibrium, has made resolving causal variants very challenging. A promising approach is to investigate gene expression levels considered ...
The major histocompatibility complex (MHC) is recognised as one of the most important genetic regions in relation to common human disease. Advancement in identification of MHC genes that confer susceptibility to disease requires greater knowledge of sequence variation across the complex. Highly duplicated and polymorphic regions of the human genome such as the MHC are, however, somewhat refract...
To the Editor: 1 work at an overseas American institution, and there are extended delays in receipt of journals by our medical library. So, it was only a few days ago that I saw the article entitled “Weak Association between HLA-B27 and the Spondylarthropies in Lebanon,” which was published in the February 1997 issue of Arthritis & Rheumatism (1). I would like to draw the attention of the Leban...
Introdouction: The aim of this study was to compare the ratios of the mesiodistal width of the upper and lower central incisors between natural teeth and those produced artificially by Ideal Makoo, Ivoclar, and Vitapan, in Iran. Materials and methods: The mesiodistal width of the upper and lower central incisors was measured in 120 students, using calipers placed at the height of contour...
The recent identification and molecular characterization of tumor-associated antigens recognized by tumorreactive CD8+ T lymphocytes has led to the development of antigen-specific immunotherapy of cancer. Among other approaches, clinical studies have been initiated to assess the in vivo immunogenicity of tumor antigenderived peptides in cancer patients. In this study, we have analyzed the CD8+ ...
PURPOSE Because the expression of classic and nonclassic HLA antigens is crucial for the recognition and elimination of tumor cells by cytotoxic T and/or NK cells, we analyzed the HLA-A, -B, -C, and -G expression in uveal melanoma specimens from 18 patients. METHODS Tumor specimens and EDTA plasma samples from 18 patients treated by primary enucleation or tumor resection for primary uveal mel...
introdouction: the aim of this study was to compare the ratios of the mesiodistal width of the upper and lower central incisors between natural teeth and those produced artificially by ideal makoo, ivoclar, and vitapan, in iran. materials and methods: the mesiodistal width of the upper and lower central incisors was measured in 120 students, using calipers placed at the height of contour of the...
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