Insulin resistance syndrome was first described by Reaven [1] as the concomitant presence of abdominal adiposity, dyslipidemia, hypertension and insulin resistance or type 2 diabetes mellitus and described this syndrome complex as syndrome X. Although researchers coined different terms to this syndrome complex [2,3], the term metabolic syndrome (MS) was coined by Adult Treatment Panel III -Nati...

OBJECTIVE Up to 30% of obese individuals are metabolically healthy. Metabolically healthy obese (MHO) individuals are characterized by having low abdominal adiposity, low inflammation level and low risk of developing metabolic comorbidity. In this study, we hypothesize that cardiorespiratory fitness (fitness) is a determinant factor for the MHO individuals and aim to investigate the association...

C hanges associated with weight gain in intensive insulin therapy are similar to those seen in insulin resistance syndrome (1). However, the effect of abdominal adiposity in type 1 diabetes has been scarcely documented, especially in women. We conducted a pilot study to document the relationships between daily insulin dose, A1C, body composition, and lipid profile in 16 young (aged 28.1 Ϯ 8.9 y...

The direction of the association between mental health and adiposity is poorly understood. Our objective was to empirically examine this link in a UK study. This is a prospective cohort study of 3 388 people (men) aged ≥ 18 years at study induction who participated in both the UK Health and Lifestyle Survey at baseline (HALS-1, 1984/1985) and the re-survey (HALS-2, 1991/1992). At both survey ex...

OBJECTIVE Inflammatory markers such as C-reactive protein (CRP) are associated with insulin resistance, adiposity, and type 2 diabetes. Whether inflammation causes insulin resistance or is an epiphenomenon of obesity remains unresolved. We aimed to determine whether first-degree relatives of type 2 diabetic subjects differ in insulin sensitivity from control subjects without a family history of...

Central adiposity, rather than body mass index (BMI), is a key pathophysiological feature of the development of obesity-related diseases. Although genetic studies by anthropometric measures such as waist circumference have been widely conducted, genetic studies for abdominal fat deposition measured by computed tomography (CT) have been rarely performed. A total of 1,243 participants who were re...

We examined the relationship between body fat and body mass index (BMI) in a multiethnic population of obese children. BMI z-scores were compared to DEXA measures of whole body composition and regional fat distribution. Fat mass index (FMI) was best predicted by the equation: 1/[(0.159- 0.013 x percentile of total abdominal fat)- (0.01 x BMI z-score)], where percentile of abdominal fat ranges f...

ABSTRACT Objective To assess the association between breakfast omission, overweight/obesity, abdominal adiposity, and unhealthy lifestyle of low-income adolescents. Methods A cross-sectional population study involving 571 public school students aged 15 19 years old. The habit having was assessed using a form, checking weekly frequency given meal considered as omission when these adolescents did...

BACKGROUND Birth weight has been shown to be positively associated with adult obesity, but relatively few studies have examined the associations with growth in specific periods of early childhood. OBJECTIVE The objective was to assess the association of measures of growth between birth and 5 y of age with adult measures of adiposity. DESIGN We conducted a longitudinal study of young adults ...

Intra-abdominal fat content is an important variable in the association between regional body fat distribution and plasma high density lipoprotein (HDL) cholesterol levels. In the present study, we report on the role of plasma postheparin lipases as well as abdominal and femoral adipose tissue lipoprotein lipase activities in the association between body fat distribution and plasma lipoprotein ...