OBJECTIVES Skin fat biopsy of the abdominal wall is a simple and safe method for detecting amyloidosis, and rectal mucosal biopsy is also frequently used for screening for the disease; however, the sensitivity of these approaches has not been fully studied. The aim of this study was to evaluate the efficacy of skin fat biopsy combined with rectal mucosal biopsy as a screening procedure for the ...

Previously, inducing inactivity for 53 h after 21 days of voluntary running resulted in a 25 and 48% increase in epididymal and omental fat pad weights, respectively, while rats continued to eat more than a group that never had access to a running wheel (J Physiol 565: 911-925, 2005). We wanted to test the hypothesis that inactivity, independent of excessive caloric intake, could induce an incr...

OBJECTIVES Emerging data suggest that several metabolic factors, released mainly by white adipose tissue (WAT) and joint tissues, and collectively named adipokines, might have a role in the pathophysiology of OA. Recently, novel adipokines such as SERPINE2, WISP2, GPNMB and ITIH5 have been identified in WAT. The main goal of this study was to analyse the expression of these novel adipokines in ...

this study was conducted to evaluate the effects of different dietary levels of full fat safflower seed (0, 5, 10, 15 and 20% of diet) on performance, carcass characteristics and selected blood metabolites of broiler chickens from arbor acres plus strain. the experiment was designed with 350 commercial one-day-old male broiler chickens using completely randomized design with 5 dietary treatment...

OBJECTIVES This study evaluated the deep-tissue pressure pain sensitivity and temporal summation of pain within and around healthy knees exposed to experimental pain. DESIGN The study was designed as a randomized crossover trial, with each subject tested on 1 day. SETTING All tests were carried out at the Laboratory for Musculoskeletal Pain and Motor Control, Center for Sensory-Motor Intera...

Even though the vascular supply of the human patella has been object of numerous studies until now, none of them has described in detail the rich arterial supply provided via the infrapatellar fat pad (of Hoffa). Therefore, we aimed to complete the knowledge about this interesting and clinically relevant topic. Five human patellae taken from voluntary body donators were studied at the Departmen...

This protocol describes a procedure to implant mammary fat pad chambers in mice. These chambers can then be used for studying breast cancer. In comparison to the classical mammary fat pad flap model, the chamber described here has the advantage of allowing multiple observation time points in the same animal with simple anesthesia.