A simple method for computing the ̄ux intensity factors associated with the asymptotic solution of elliptic equations having a large convergence radius in the vicinity of singular points is presented. The Poisson and Laplace equations over domains containing boundary singularities due to abrupt change of the boundary geometry or boundary conditions are considered. The method is based on approxim...

An advantage for some wide bandgap materials, that is often overlooked, is that the thermal coefficient of expansion (CTE) is better matched to the ceramics in use for packaging technology. It is shown that the optimal choice for uni-polar devices is clearly GaN. It is further shown that the future optimal choice for bipolar devices is C (diamond) owing to the large bandgap, high thermal conduc...

There is an urgent need for accurate prediction of climate change impacts on species ranges. Current reliance on bioclimatic envelope approaches ignores important biological processes such as interactions and dispersal. Although much debated, it is unclear how such processes might influence range shifting. Using individual-based modelling we show that interspecific interactions and dispersal ab...

BACKGROUND The aim of this study was to examine if gradual withdrawal of remifentanil infusion prevented opioid-induced hyperalgesia (OIH) as opposed to abrupt withdrawal. OIH duration was also evaluated. METHODS Nineteen volunteers were enrolled in this randomized, double-blinded, placebo-controlled, crossover study. All went through three sessions: abrupt or gradual withdrawal of remifentan...